| HPLC-MS/MS法测定安神类代用茶中19种镇静安神类非法添加物质 |
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| 引用本文： | 刘国姣,王彬,曾妮,江丰,吴婉琴,王会霞,郭晓希,张苗.HPLC-MS/MS法测定安神类代用茶中19种镇静安神类非法添加物质[J].食品研究与开发,2019(18):187-193. |
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| 作者姓名： | 刘国姣 王彬 曾妮 江丰 吴婉琴 王会霞 郭晓希 张苗 |
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| 作者单位： | 湖北省食品质量安全监督检验研究院;湖北省食品质量安全检测工程技术研究中心 |
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| 摘 要： | 建立一种快速测定安神类代用茶中19种镇静安神类非法添加物的高效液相色谱-串联质谱(high performance liquid chromatography-tandem mass spectrometry,HPLC-MS/MS)的检测方法。样品经乙腈提取后,以ACE Excel 2 C18(100×2.1 mm,1.7μm)为色谱柱,甲醇~0.1%甲酸为流动相进行梯度洗脱,采用多反应监测正离子模式对19种非法添加物质同时进行定性定量分析。结果表明,19种分析物在其相应的浓度范围内峰面积与质量浓度呈良好的线性关系,相关系数(R2)均大于0.99,该方法的检出限为10μg/kg^200μg/kg,定量限为30μg/kg^600μg/kg,样品的回收率为80.5%~108.8%。该方法可应用到安神类代用茶中19种镇静安神类非法添加物的定量分析检测。
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| 关 键 词： | 镇静安神 代用茶 非法添加物 高效液相色谱-质谱法(HPLC-MS/MS) |
Simultaneous Determination of 19 Kinds of the Illegally Added Drugs in Herbal Tea by High Performance Liquid Chromatography-Tandem Mass Spectrometry |
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| LIU Guo-jiao,WANG Bin,ZENG Ni,JIANG Feng,WU Wan-qin,WANG Hui-xia,GUO Xiao-xi,ZHANG Miao.Simultaneous Determination of 19 Kinds of the Illegally Added Drugs in Herbal Tea by High Performance Liquid Chromatography-Tandem Mass Spectrometry[J].Food Research and Developent,2019(18):187-193. |
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| Authors: | LIU Guo-jiao WANG Bin ZENG Ni JIANG Feng WU Wan-qin WANG Hui-xia GUO Xiao-xi ZHANG Miao |
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| Affiliation: | (Hubei Provincial Institute for Food Supervision and Test, Wuhan 430075, Hubei, China;Hubei Provincial Engineering and Technology Research Center for Food Quality and Safety Test,Wuhan 430075, Hubei, China) |
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| Abstract: | LIU Guo-jiao;WANG Bin;ZENG Ni;JIANG Feng;WU Wan-qin;WANG Hui-xia;GUO Xiao-xi;ZHANG Miao(Hubei Provincial Institute for Food Supervision and Test, Wuhan 430075, Hubei, China;Hubei Provincial Engineering and Technology Research Center for Food Quality and Safety Test,Wuhan 430075, Hubei, China) |
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| Keywords: | phenobarbital herbal tea illegally added drugs high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS) |
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