采用喷墨打印机进行低成本微阵列印刷的可行性研究

根据网点形成技术,微阵列制作方法可归结为接触式印刷和非接触式印刷.接触式印刷中,如印刷生物样本时,设备与基底是直接接触.而非接触式印刷中,设备与基底之间不会直接接触.在非接触式印刷中,喷墨印刷技术是相对灵活、简便、便宜的一种方式,同时还减少了污染且避免了更高的数据吞吐量.但是,喷墨印刷需要有能喷射儿微微升墨滴的喷嘴和能够精确喷射墨滴的喷嘴位置控制单元.若使用喷墨方法制作微阵列就需要复杂的机构系统,以致成本增加.因此,本论文提出使用已具有喷墨系统的商用喷墨打印机来制作微阵列.

Feasibility of Low-Cost Microarray Printing with Inkjet Printer

The methods of microarray fabrication are categorized as contact printing and non-contact printing according to spot formation techniques. In contact printing, a printing device does physical contact at the substrate while depositing biological sample. In contrast, non-contact printing involves no physical contact between the device and the substrate.In non-contact printing, inkjet printing technology is relatively flexible, simple and less expensive, also reduced contamination and higher throughput. For inkjet printing, however, need nozzles that can eject several pl(pico-litter)volumes and the position control of nozzle to eject ink with accurate position. These necessities complicate organization of the system that can fabricate microarray using inkjet method, and increase costs. Therefore, this paper proposes such a microarray fabrication methodology using a commercial inkjet printer that is already consisting of ink ejection system.