| 碳硼烷及其在核医学领域的应用研究进展 |
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| 引用本文： | 陈文,魏洪源,罗顺忠.碳硼烷及其在核医学领域的应用研究进展[J].同位素,2011,24(4):234-239. |
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| 作者姓名： | 陈文 魏洪源 罗顺忠 |
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| 作者单位： | 中国工程物理研究院 核物理与化学研究所，四川 绵阳621900 |
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| 基金项目： | 中国工程物理研究院科学技术发展基金(2010B0301036) |
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| 摘 要： | 碳硼烷由于其特殊的热稳定性和化学稳定性，在超分子化学，催化剂和药物先导等多领域已成为研究热点。近几年，碳硼烷从作为传统的硼中子俘获治疗（Boron Neutron Capture Therapy，BNCT）药物拓展到临床放射性分子成像和治疗，其在核医学领域的发展呈多样化的趋势。本文在简要介绍碳硼烷的合成和性质的基础上，对其在核医学领域的应用研究进展进行综述。
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| 关 键 词： | 碳硼烷 核医学 研究进展 |
Research Advancements and Applications of Carboranes in Nuclear Medicinal Chemistry |
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| CHEN Wen,WEI Hong-yuan,LUO Shun-zhong.Research Advancements and Applications of Carboranes in Nuclear Medicinal Chemistry[J].Isotopes,2011,24(4):234-239. |
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| Authors: | CHEN Wen WEI Hong-yuan LUO Shun-zhong |
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| Affiliation: | Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900, China |
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| Abstract: | Because of their uniquely high thermal and chemical stabilities,carboranes have become a subject of study with high interest in the chemistry of supramolecules,catalysts and radiopharmaceuticals.In recent years,the role of carboranes in nuclear medicinal chemistry has been diversified,from the traditional use in boron neutron capture therapy(BNCT),to the clinical applications in molecular radioimaging and therapy.This paper provides an overview of the synthesis and characterization of carboranes and their a... |
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| Keywords: | carboranes nuclear medicine advanced ment |
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