甲状腺^131I率的测定对鉴别诊断甲亢^131I治疗后早发甲低类型的临床意义

通过测定甲状腺吸^131I率鉴别诊断^131I治疗后早发甲低的类型。63例甲亢^131I治疗后早发甲低的患者（一过性甲低组33例，永久性甲低组30例，）在甲状腺替代隍、6个月测定甲状3h吸^131I率和血清TT3、TT4、TSH浓度。结果表明：治疗前一过性与永久性甲低组间^131I率有明显差异，TT3、TT4、TSH浓度无明显差异；对对照组相比，一过性甲低组低组治疗前吸^131I率无差异，TT3、TT4和TSH浓度有明显差异，治疗后均无差异；永久性甲低组吸^131I率治疗前、后均明显降低。因此早发甲低的患者，仅靠TT3、TT4、TSH水平难以鉴别甲低类型；但根据吸^131I可准确判断，即甲状腺3h^131I率正常，可以判断为一过性甲低，反之则为永久性甲低。

The Clinical Significance of Measuring the Thyroid 131I Uptake Rate to Identify the Type of Premature Hypothyroidism for Hyperthyroid After 131I Treatment

The 3 h thyroid 131I uptake rate and the content of serum TT3,TT4,TSH are measured in 63 patients of premature hypothyroidism (consiting of 33 provisional pypothyroids and 30 perpetual hypothyroidism) before and after thyroxine substitutes treatment for six moths. The results show that there is obvious difference in 131I uptake rate compared provisional hypothyroidism with perpetual hypothyroidism, and no difference in the content of serum TT3,TT4,TSH before the treatment. Compared with normal conditions, there is no difference in 131I uptake rate of provisional hypothyroidism, but the 131I uptake rate of perpetual hypothyroidism has obvious decrease before and after the treatment. Therefore the type of patients who suffer from premature hypothyroidism can be distinguished according to the 131I uptake rate:if the 3 h thyroid 131I uptake rate is normal,it is provisional hypothyroidism;if not,it is perpetual hypothyroidism.