布比卡因伍用地塞米松对硬膜外阻滞效果的影响

目的 观察布比卡因伍用地塞米松与单用布比卡因对硬膜外阻滞效果的影响。方法 选择下肢显微外科手术病人120 例, 随机双盲分成4 组, Ⅰ组为对照组, Ⅱ~Ⅳ组为观察组, 每组30 例。均用0.75%布比卡因1.4 mg·kg^-1, Ⅱ~Ⅳ组分别伍用地塞米松0.075、0.15、0.3mg·kg^-1 行硬膜外阻滞, 对比观察麻醉和镇痛时间。结果 与对照组比, 观察组起效时间快, 阻滞完善和镇痛时间长(P<0.01)。结论 布比卡因伍用地塞米松用于硬膜外阻滞, 其效果优于单用布比卡因。

Influence of bupivacaine combined with dexamethesone on epidural blockade

Aim The efficacy of bupivacaine administered alone or in combination with dexamethesone in epidural blockade was observed.Methods 120 cases of microsurgical operation in lower extremities were randomly divided intofour groups in double blind form,.The bupivacaine (0.75%, 1.4 mg/kg) was administered alone in the control group(A) and in combination with different doses of dexamethesone(0.075、0.15、0.3 mg/kg)in the test groups (B,C and D)respectively.The anesthetic time, postoperative analgesic time and the effect of neuromuscular blockade in each group were compared.Results The onset time in the test groups was shorter than that in the control group, and the anesthetic time and postoperative analgesic time in the test groups were longer than those in the control group. Conclusion The efficacy of bupivaceine combined with dexamethesone was superior to that of it alone in epidural blockade.