| 纳滤选择性分离丁二酸模拟发酵液 |
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| 引用本文： | 吴昊,姜岷,韦萍,高超,杨高,雷丹.纳滤选择性分离丁二酸模拟发酵液[J].膜科学与技术,2011,31(5):46-51. |
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| 作者姓名： | 吴昊 姜岷 韦萍 高超 杨高 雷丹 |
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| 作者单位： | 南京工业大学制药与生命科学学院,材料化学工程国家重点实验室,南京210009 |
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| 基金项目： | 国家“973”计划项目(2009CB724701); 江苏省高校自然科学基础研究资助项目(08KJB180003); 南京工业大学青年教师学术基金; 江苏省“六大人才高峰”资助项目(06-A-047) |
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| 摘 要： | 生物法制备的丁二酸发酵液中含有残留的底物(葡萄糖)、甲酸、乙酸及二价无机离子(Mg2+、SO42-)等杂质,不利于分离纯化.采用截留相对分子质量为160的纳滤膜LNG-NF-016对丁二酸模拟发酵液进行分离,考察了pH、操作压力、MgSO4浓度、丁二酸浓度、葡萄糖浓度、料液体积流量、操作温度等因素对纳滤分离性能的影响....
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| 关 键 词： | 丁二酸 纳滤 选择性分离 模拟发酵液 |
Selective separation of succinic acid from simulated fermentation broth by nanofiltration |
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| WU Hao,JIANG Min,WEI Ping,GAO Chao,YANG Gao,LEI Dan.Selective separation of succinic acid from simulated fermentation broth by nanofiltration[J].Membrane Science and Technology,2011,31(5):46-51. |
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| Authors: | WU Hao JIANG Min WEI Ping GAO Chao YANG Gao LEI Dan |
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| Affiliation: | WU Hao,JIANG Min,WEI Ping,GAO Chao,YANG Gao,LEI Dan(State Key Laboratory of Materials-Oriented Chemical Engineering,College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing 210009,China) |
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| Abstract: | Many impurities existed in succinic acid fermentation broth,such as by-product organic acids(formic acid,acetic acid),residual substrate(glucose) and divalent ion(Mg2+,SO42-),which was unfavorable to purification.Separation of succinic acid from simulated fermentation broth by nanofiltration membrane LNG-NF-016(MWCO 160) was studied,For this purpose,the effect of operating parameters such as pH in the feed solution,operation pressure,MgSO4 concentration,succinic acid concentration,glucose concentration,cros... |
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| Keywords: | succinic acid nanofiltration selective separation simulated fermentation broth |
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