| 陶瓷膜超滤在丁二酸发酵液纯化中的应用 |
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| 引用本文： | 余作龙,姜岷,吴昊,陈可泉,韦萍.陶瓷膜超滤在丁二酸发酵液纯化中的应用[J].膜科学与技术,2010,30(2). |
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| 作者姓名： | 余作龙 姜岷 吴昊 陈可泉 韦萍 |
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| 作者单位： | 南京工业大学,制药与生命科学学院,材料化学工程国家重点实验室,南京,210009 |
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| 基金项目： | 国家高技术研究发展计划资助项目(“863”计划)(2006AA02Z235);;国家自然科学基金资助项目(20606017);;江苏省高技术研究计划(BG2007001) |
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| 摘 要： | 对陶瓷膜过滤丁二酸发酵液的条件进行研究.考察在不同压差下,发酵液的pH以及浓缩倍数对膜通量的影响,并对膜清洗条件进行选择.结果表明在0.3 MPa压差下,发酵液调节pH至4.5,可获得最大膜通量,浓缩到7倍最佳.菌体截留率达到98.37%,蛋白质去除率为89.67%,总有机碳下降约40%.而膜污染后先后用1%次氯酸钠,1%氢氧化钠+0.5%EDTA清洗,可以恢复膜通量.实验表明,可以将陶瓷膜用于分离丁二酸发酵液,有利于简化操作步骤,提高生产效率.
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| 关 键 词： | 陶瓷膜 丁二酸发酵液 膜分离 膜清洗 |
Application of ceramic membrane ultrafiltation purify succinic acid fermentation broth |
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| YU Zuolong,JIANG Min,WU Hao,CHEN Kequan,WEI Ping.Application of ceramic membrane ultrafiltation purify succinic acid fermentation broth[J].Membrane Science and Technology,2010,30(2). |
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| Authors: | YU Zuolong JIANG Min WU Hao CHEN Kequan WEI Ping |
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| Affiliation: | State Key Laboratory of Materials-Oriented Chemical Engineering/a>;College of Life Science and Pharmaceutical Engineering/a>;Nanjing University of Technology/a>;Nanjing 210009/a>;China |
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| Abstract: | The conditions of ultrafiltrate succinic acid by ceramic membrane was researched.The influences of pressure,pH and concentration ratio of fermentation on the membrane flux were studied.The optimal membrame cleaning methods were chosen.The result showed that under pressure 0.3 MPa and the fermentation broth of pH 4.5,the maximum membrane flux was attained.The cell retention rate of 98.73% retained,the removal of protein was 89.67%,and the contain of the total organic carbon declined about 40%,respectively.Fo... |
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| Keywords: | ceramic membrane succinic acid fermentation membrane separation membrane cleaning |
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