基于超材料的无标记光学生物传感

超材料(metamaterials)因为能够在亚波长尺度范围内精细调控电磁波而受到人们广泛关注。超材料具有丰富的电磁模态,在表面支持高度局域场增强且对周围介电环境极其敏感,可应用于无标记光学生物传感领域。与传统光学生物传感器相比,超材料生物传感器具有小型化、集成化、高度灵敏、多功能可定制等突出优点。本文总结了近年来超材料生物传感器在可见光、近红外、中红外以及太赫兹波段的研究进展,包括折射率生物传感、表面增强拉曼散射、表面增强红外吸收和太赫兹生物传感等。

Metamaterial-based label-free optical biosensing

Metamaterials have drawn extensive attention for their fine regulation of electromagnetic waves at subwavelength scales.They have abundant electromagnetic modes,and support highly confined and enhanced electromagnetic fields on the surface which are highly sensitive to the surrounding dielectric environment,so they can be used in label-free optical biosensing.Compared with traditional optical biosensors,metamaterial biosensors have many advantages,such as miniaturization,integration,high sensitivity and multi-function customization.The recent progress of metamaterial biosensors in visible light and near infrared,middle infrared,and terahertz spectrums was summarized in this paper,including refractive index biosensing,surface-enhanced Raman scattering,surface-enhanced infrared absorption,and terahertz biosensing.