| 空心羟基磷灰石亚微球/壳聚糖可注射水凝胶的制备及表征 |
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| 引用本文： | 李湘南,陈晓明,彭志明,李世普.空心羟基磷灰石亚微球/壳聚糖可注射水凝胶的制备及表征[J].功能材料,2011,42(2):206-209,213. |
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| 作者姓名： | 李湘南 陈晓明 彭志明 李世普 |
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| 作者单位： | 武汉理工大学生物材料与工程研究中心;武汉理工大学化工学院; |
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| 基金项目： | 国家自然科学基金资助项目(50872099) |
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| 摘 要： | 采用W/O/W复乳法制备空心羟基磷灰石(HAP)亚微球,将空心HAP亚微球均匀分布在壳聚糖/甘油磷酸钠(CS/GP)体系中制备可注射HAP/CS水凝胶(gel 1),同时制备可注射CS水凝胶(gel 2).用X射线衍射仪、场发射透射电镜、红外光谱、扫描电镜对空心HAP亚微球和水凝胶进行了表征,并比较分析了两种溶胶的成胶...
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| 关 键 词： | 羟基磷灰石 空心亚微球 壳聚糖 可注射水凝胶 |
Preparation and characterization of hollow hydroxyapatite submicrospheres/chitosan injectable hydrogels |
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| LI Xiang-nan,CHEN Xiao-ming,PENG Zhi-ming,LI Shi-pu.Preparation and characterization of hollow hydroxyapatite submicrospheres/chitosan injectable hydrogels[J].Journal of Functional Materials,2011,42(2):206-209,213. |
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| Authors: | LI Xiang-nan CHEN Xiao-ming PENG Zhi-ming LI Shi-pu |
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| Affiliation: | LI Xiang-nan1,2,CHEN Xiao-ming1,PENG Zhi-ming1,LI Shi-pu1(1.Biomedical Materials and Engineering Research Center,Wuhan University of Technology,Wuhan 430070,China,2.College of Chemical Engineering,China) |
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| Abstract: | Hollow hyroxyapatite(HAP) submicrospheres were prepared by a W/O/W multiple emulsion method,HAP/chitosan hydrogels were developed by filling hollow HAP submicrospheres with chitosan/glycerol-phosphate(CS/GP) solutions,and chitosan hydrogels were also prepared.The composition and morphology of the products were analyzed by XRD,TEM,FT-IR and SEM,gel formation time,stability and compressive strength of the two hydrogels were measured.The results showed hollow HAP submicrospheres with diameter of approximately ... |
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| Keywords: | hydroxyapatite hollow submicrospheres chitosan injectable hydrogels |
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