| S-腺苷甲硫氨酸制备方法的研究进展 |
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| 引用本文： | 牛卫宁,左晓佳,王丽衡,钦传光.S-腺苷甲硫氨酸制备方法的研究进展[J].化学与生物工程,2009,26(3). |
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| 作者姓名： | 牛卫宁 左晓佳 王丽衡 钦传光 |
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| 作者单位： | 西北工业大学生命科学院,陕西,西安,710072 |
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| 基金项目： | 国家自然科学基金，中国博士后科学基金，西北工业大学青年科技创新基金，西北工业大学科技创新基金 |
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| 摘 要： | S-腺苷甲硫氨酸(SAM)是生物体内重要的生理活性物质,参与多种生化反应,临床上被广泛用于治疗抑郁症、神经紊乱、肝病、关节炎等.综述了SAM制备方法的研究进展,述及的SAM制备方法包括化学合成法、微生物发酵法、体外酶促合成法以及全细胞催化法.
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| 关 键 词： | S-腺苷甲硫氨酸 微生物发酵法 体外酶促合成法 全细胞催化 |
Development for the Preparation of S-Adenosylmethionine |
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| NIU Wei-ning,ZUO Xiao-jia,WANG Li-heng,QIN Chuan-guang.Development for the Preparation of S-Adenosylmethionine[J].Chemistry & Bioengineering,2009,26(3). |
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| Authors: | NIU Wei-ning ZUO Xiao-jia WANG Li-heng QIN Chuan-guang |
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| Abstract: | S-Adenosylmethionine(SAM) is an important bioactive substance in organism which is involved in many biochemical reactions.SAM has been widely used for the treatment of depression,neurologic disorders,liver disease and osteoarthritis.The development for the preparation of SAM was reviewed,and the methods including chemical synthesis,microbial fermentation,enzymatic reaction in vitro and whole-cell catalysis were discussed. |
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| Keywords: | S-adenosylmethionine microbial fermentation enzymatic reaction in vitro whole-cell catalysis |
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