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生物分析用近红外荧光染料研究进展
引用本文:施锋,李宏洋,彭孝军.生物分析用近红外荧光染料研究进展[J].精细化工,2003,20(5):268-272.
作者姓名:施锋  李宏洋  彭孝军
作者单位:大连理工大学,精细化工国家重点实验室,辽宁,大连,116012
基金项目:国家重点基础研究专项经费资助,国家自然基金资助(项目批准号:20128005)~~
摘    要:概述了用于生物分析领域与生物分子共价结合的近红外荧光染料,包括菁染料(含多次甲基菁、方酸菁和克酮酸染料)、酞菁、罗丹明及荧光素等,对其结构、光谱性能、应用等方面进行了综述,对发展前景进行了预测。

关 键 词:近红外荧光染料  共价结合标记  DNA
文章编号:1003-5214(2003)05-0268-05

Developments of Fluorescent Dyes for Biochemistry
SHI Feng,LI Hong-yang,PENG Xiao-jun chnology,Dalian ,Liaoning,China.Developments of Fluorescent Dyes for Biochemistry[J].Fine Chemicals,2003,20(5):268-272.
Authors:SHI Feng  LI Hong-yang  PENG Xiao-jun chnology  Dalian  Liaoning  China
Affiliation:SHI Feng,LI Hong-yang,PENG Xiao-jun chnology,Dalian 116012,Liaoning,China)
Abstract:Due to the requirement of near infrared fluorescent dyes in biochemistry,this paper focused on the research progress of NIR dyes,and some suggestions were put forward on the future research.This paper mainly introduced dyes which are used for covalent labeling of chemically modified nucleic acids,and paid attention to the properties such as maximum absorption wavelength and the absorption intensity.Attention was paid to the near infrared fluorescent dyes as follows:cyanine dyes which included polymethine dyes,squarylium and croconium dyes,phthalocyanines,rhodamines and fluoresceins.
Keywords:near infrared fluorescent dyes  covalent label  DNA
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