| 相转移催化合成2,4-二氯苯氧乙酸新工艺研究 |
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| 引用本文： | 杜剑萍,邵山,吴军.相转移催化合成2,4-二氯苯氧乙酸新工艺研究[J].化学工业与工程技术,2012,33(6):15-17. |
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| 作者姓名： | 杜剑萍 邵山 吴军 |
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| 作者单位： | 1. 常州永泰丰化工有限公司,江苏常州,213033
2. 常州新东化工发展有限公司,江苏常州,213033 |
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| 摘 要： | 以2,4-二氯苯酚和氯乙酸为原料,在碳酸钾作用下筛选相转移催化剂(四丁基溴化铵、四乙基溴化铵和PEG-600)进行醚化反应,制备2,4-二氯苯氧乙酸。所获得的最佳工艺条件是:催化剂选PEG-600/KI为最佳,二氯苯酚和氯乙酸原料物质的量比1∶2,相转移催化剂PEG-600用量为二氯苯酚的6%,KI用量为二氯苯酚量的10%。在此合成条件下,2,4-二氯苯氧乙酸收率达94.2%。
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| 关 键 词： | 2 4-二氯苯氧乙酸 相转移催化剂 氯乙酸 2 4-二氯苯酚 |
Phase transfer catalytic synthesis of 2,4-dichlorophenoxyacetic acid |
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| DU Jianping
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SHAO Shan
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WU Jun.Phase transfer catalytic synthesis of 2,4-dichlorophenoxyacetic acid[J].Journal of Chemical Industry & Engineering,2012,33(6):15-17. |
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| Authors: | DU Jianping SHAO Shan WU Jun |
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| Affiliation: | 1(1.Changzhou Wintafone Chemical Co.,Ltd.,Changzhou 213033,China; 2.Changzhou Xindong Chemical Industry Development Co.,Ltd.,Changzhou 213033,China) |
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| Abstract: | 2,4-Dichlorophenoxy acetic acid is synthesized by etherification of chloroacetic acid and 2,4-dichlorophenol with phase transfer catalyst which selected from tetrahutylammonium bromide （TBAB）, tetraethylammonium bromide （TEAB） and polyethylene gtycol-600 （PEG-600） by potassium carbonate. The effect of different catalysts on yield of 2,4-dichlorophenoxy acetic acid is studied. As a result, the optimal conditions are obtained as following= using PEG-600/KI as the most suitable cat- alyst, the molar ratio of 2,4-dichlorophenol, chloroacetic acid, PEG-600 and KI is 1： 2 ： 0.06 ： 0.1. Under these conditions, the yield of 2,4-dichlorophenoxy acetic acid reaches 94.2%. |
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| Keywords: | 2 4-Dichlorophenoxy acetic acid Phase transfer catalysis （PTC） Chloroacetic acid 2 4-dichlorophenol |
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