Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications |
| |
| Authors: | Dr Md Kausar Raza Aisha Noor Dr Paresh Kumar Samantaray |
| |
| Affiliation: | 1. Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125 USA;2. Department of Biotechnology, Jamia Millia Islamia, New Delhi, 110025 India |
| |
| Abstract: | Individually, photoredox catalysis (PC) and photodynamic therapy (PDT) are well-established concepts that have experienced a remarkable resurgence in recent years, leading to significant progress in organic synthesis for PC and clinical approval of anticancer drugs for PDT. But, very recently, new photoredox catalyst systems based on Ir(III) and Ru(II) complexes have garnered significant interest because they can simultaneously be used as PDT agents apart from their demonstrated PC activity. This highlight discusses the unique PC behavior of emerging Ir(III)- and Ru(II)-based systems while also examining their potential PDT activity in cancer treatment. |
| |
| Keywords: | anticancer treatment Ir(III) and Ru(II) complexes photodynamic therapy photoredox catalysis |
|
|
