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吡唑联吡唑化合物库的液相平行合成
引用本文:任雪玲,胡方中,邹小毛,杨华铮.吡唑联吡唑化合物库的液相平行合成[J].农药,2003,42(6):17-18,13.
作者姓名:任雪玲  胡方中  邹小毛  杨华铮
作者单位:南开大学元素有机化学国家重点实验室,元素有机化学研究所,天津,300071
摘    要:吡唑联吡唑类化合物是一类高效的除草剂,其生物活性的体现与其取代基有着密切联系。为了更好地了解吡唑联吡唑化合物的构效关系以及发现新的先导化合物,我们将传统有机合成与平行液相组合合成有机结合,合成了吡唑联吡唑化合物库。每个化合物子库均经过核磁共很、元素分析和液语或GCD确证。

关 键 词:吡唑联吡唑  化合物库  合成  除草剂  平行液相组合合成

Parallel- Liquid - Phase Synthesis of a Library Containing Substituted Pyrazolypyrazoles
Ren Xueling,Hu Fangzhong,Zou Xiaomao,Yang Huazheng.Parallel- Liquid - Phase Synthesis of a Library Containing Substituted Pyrazolypyrazoles[J].Pesticides,2003,42(6):17-18,13.
Authors:Ren Xueling  Hu Fangzhong  Zou Xiaomao  Yang Huazheng
Abstract:Prompted by the observation that many pyrazolypyrazole derivatives are used as herbicides.A small combinatorial library containing pyrazolypyrazole derivatives was synthesized by traditional organic synthesis and parallel-liquid-phase combinatorial synthesis.New lead compounds were expected to be discoveried through this library.The structures of compounds were confirmed by 1 HNMR?LC and elementary analysis.
Keywords:pyrazolypyrazole  parallel-liquid-phase synthesis  combinatorial library  synthesis  herbicide    
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