以葡萄糖为造孔剂制备多孔羟基磷灰石涂层

采用电泳沉积方法在钛基材表面制得羟基磷灰石(hydroxyapatite,HA)/葡萄糖复合涂层,经烧结处理得到多孔HA涂层。采用红外光谱仪、扫描电镜、X射线衍射和热重分析表征了涂层的组成、表面形貌、物相组成及热稳定性,黏结-拉伸实验测定涂层与基体的结合强度,人体模拟体液(simulated body fluid,SBF)浸泡测定涂层的生物亲合性。结果表明:经700℃烧结处理,复合涂层中的葡萄糖微粒热分解得到多孔HA涂层,孔径为2～20μm,涂层与基体的结合强度可达17.6MPa;在1.5倍SBF(各离子浓度为SBF的1.5倍)中浸泡5d后,多孔HA涂层表面碳磷灰石化,呈现良好的生物亲合性。

PREPARATION OF POROUS HYDROXYAPATITE COATING WITH GLUCOSE AS PORE PRODUCER

Hydroxyapatite (HA)/glucose composite coating was deposited on titanium substrate hy electrophoretic deposition, and then a porous HA coating was obtained by sintering. The chemical composition, surface morphology, phase composition, and thermal stability of the porous HA coating were characterized by infrared spectrometry, scanning electron microscopy, X-ray diffraction and thermogravimetric analysis. The bonding strength between the coating and substrate was measured by a stretcher shear test; the bio-affinity of the coating was determined by immersion in simulated body fluid (SBF). The results show that the pore diameter of the porous HA coating sintered at 700℃ is about 2-20μm, and its bonding strength can reach 17.6 MPa. The surface of the coating is carbonate-apatite covered after immersion in 1.5 SBF (the concentrations of ions in the 1.5 SBF are 1.5 times as high as the SBF) for 5 d, indicating that it has good bio-affinity.