Bioactivity behaviour of biodegradable material comprising bioactive glass |
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Authors: | Xuan Vuong Bui Hassane Oudadesse Yann Le Gal Odile Merdrignac-Conanec Guy Cathelineau |
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Affiliation: | (1) Department of Materials Science & Metallurgy, University of Cambridge, New Museums Site, Pembroke Street, Cambridge, CB2 3QZ, UK; |
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Abstract: | Biocomposite of bioactive glass (BG) with chitosan polymer (CH) is prepared by freeze-drying technique. Obtained material
is investigated by using several physico-chemical methods. The XRD and FTIR show the interface bonding interactions between
glass and polymer. The specific surface and porosity of biocomposite were determined. In vitro assays were employed to evaluate the effect of chitosan addition on the glass by studying the chemical reactivity and bioactivity
of the BG and BG/CH biocomposite after soaking in a simulated body fluid (SBF). The obtained results show the formation of
a bioactive hydroxycarbonate apatite (HCA) layer and highlight the bioactivity and the kinetics of chemical reactivity of
bioactive glass, particularly after association with chitosan. The BG/CH biocomposite has excellent ability to form an apatite
layer. Inductively coupled plasma-optical emission spectrometry (ICP-OES) highlights the negative effect of chitosan on the
silicon release toward the SBF of bioactive glass when in vitro assays. |
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