| 数学建模与仿真在光动力疗法研究中的应用 |
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| 引用本文： | 程刚,钟秋海.数学建模与仿真在光动力疗法研究中的应用[J].四川激光,2006,27(1):84-85,87. |
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| 作者姓名： | 程刚 钟秋海 |
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| 作者单位： | 北京理工大学自动控制系,北京100081 |
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| 摘 要： | 采用建模和仿真方法，建立光动力疗法（Photodynamic Therapy，PDT）微血管效应的系统模型，可以分析出光动力疗法对组织的损伤机制及各个因素的作用关系和作用规律，辅助医生进行临床治疗和决策。本文综述了在建立光动力疗法微血管效应数学模型研究中所涉及到的组织光学、药代动力学、光化学等研究领域的研究方法和研究结果及其在模型中的作用。
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| 关 键 词： | 光动力疗法 数学建模 组织光学 药代动力学 光化学 |
| 文章编号： | 0253-2743（2006）01-0084-02 |
| 收稿时间： | 2004-04-05 |
| 修稿时间： | 2004-04-05 |
Application of mathematic modeling and simulation in photodynamic therapy research |
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| CHENG Gang,ZHONG Qiu-hai.Application of mathematic modeling and simulation in photodynamic therapy research[J].Laser Journal,2006,27(1):84-85,87. |
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| Authors: | CHENG Gang ZHONG Qiu-hai |
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| Affiliation: | Department of Automatic Control, Beijing Institute of Technology, Beijing 100061, China |
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| Abstract: | To study the acting factors on vascular selectivity of photodynamic therapy, the mathematic modeling of vascular selectivity of photodynamic therapy is achieved. The modeling can help doctors to diagnose and analyze the clinical cases. Many research fields are involved in the modeling, such as tissue optics, pharmacokinetics and photochemistry. The application of these fields in the modeling is review in this paper. |
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| Keywords: | mathematic modeling tissue optics pharmacokinetics photochemistry |
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