硼污染的个人暴露剂量及其代谢的研究

 以62名处于不同生活、工作环境下的人群为对象,研究了其通过空气粉尘、饭菜和饮水的日硼暴露剂量及通过尿液、粪便的代谢状况.结果表明,从事硼作业的53名工人日硼暴露均值11.8mg/d,是对照人群(1.52mg/d)的7.8倍;通过尿液代谢的硼占总代谢量的94%以上,且班后尿硼与24h全尿硼浓度的相关系数为0.952,班后尿样可代替全尿并反映硼的代谢水平;下班后尿硼浓度与日硼暴露剂量显著相关.多元线性回归可以反映不同暴露途径对尿硼水平的贡献,方程拟合度为43.0%,与实测值的平均相对偏差为23.6%.

Individual exposure dosage of boron pollution and its metabolism

Daily exposure dosage of boron through air-dust, food and drinking water and through urine and excrementmetabolism state were reported with the crowd of 62 persons under different living and working environment as researchobjects. The average daily exposure dosage of boron among 53 workers was 11.8mg/d being 7.8 times of that amongcontrol group of 1.52mg/d; the boron through urine metabolism was more than 94% of total amount of the metabolism;boron concentration of after-shift urine and that of 24h urine were correlated with coefficient of 0.952; after-shift urinesample could stand for that of 24h urine and reflect boron metabolism level; there was remarkable correlation betweenboron concentration of after-shift urine and daily exposure dosage of boron; multiple linear regressions could reflect morethe contribution of different ways of exposure to the boron level in urine, with equation fitting rate of 43.0%. The averageof relative deviation between the urine boron concentrations predicted with regression equation and actual the measuredvalue was 23.6%.