| 广州市大气NO2污染对暴露人群不同疾病死亡的影响 |
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| 引用本文： | 蔡东杰,杨军,黄琳,陈素娟,赵文龙,董航,林国帧,王伯光.广州市大气NO2污染对暴露人群不同疾病死亡的影响[J].中国环境科学,2022,42(8):3950-3956. |
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| 作者姓名： | 蔡东杰 杨军 黄琳 陈素娟 赵文龙 董航 林国帧 王伯光 |
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| 作者单位： | 1. 暨南大学环境与气候研究院, 广东 广州 511443;2. 广州医科大学公共卫生学院, 广东 广州 511436;3. 广州市疾病预防控制中心, 广东 广州 510440;4. 粤港澳环境质量协同创新联合实验室, 广东 广州 511443;5. 暨南大学-昆士兰科技大学空气质量科学与管理联合实验室, 广东 广州 511443 |
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| 基金项目： | 国家自然科学基金资助项目(82003552)；;广东省基础与应用基础研究基金项目(2020A1515011161)；;国家重点研发计划项目(2018YFC0213600)； |
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| 摘 要： | 通过收集广州市2011~2015年6种疾病（非意外因素、心血管疾病、脑卒中、缺血性心脏病、呼吸系统疾病以及慢性阻塞性肺疾病）逐日死亡人数、逐日NO2浓度以及同期气象资料，采用广义相加模型探讨了NO2暴露对不同疾病死亡的影响（相对危险度，RR值）和累积滞后效应，并进一步采用分层分析方法解析了冷季（11月至次年4月）和暖季（5~10月） NO2死亡风险的差异.结果表明，NO2影响急促短暂，通常持续4d.当NO2浓度升高10μg/m3，在Lag0-4d时，人群非意外死亡人数将上升2.18%（RR=1.0218；95% CI：1.0167，1.0270），在冷季与暖季分别上升2.6%（RR=1.0260；95% CI：1.0191，1.0328）与0.57%（RR=1.0057；95% CI：0.9952，1.0163），两者差异有统计学意义（P=0.002）.在不同疾病中，NO2对慢性阻塞性肺疾病的影响最大.因而NO2仍然为广州地区人群健康重要的危险因素，需要加强NO2排放的控制与治理，并且加强冷季健康风险预警以保护公共健康.
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| 关 键 词： | NO2 逐日死亡人数 健康风险 广义相加模型 季节效应 |
| 收稿时间： | 2022-01-24 |
Impacts of atmospheric NO2 pollution on cause-specific mortality of different diseases in exposed population in Guangzhou |
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| CAI Dong-jie,YANG Jun,HUANG Lin,CHEN Su-juan,ZHAO Wen-long,DONG Hang,LIN Guo-zhen,WANG Bo-guang.Impacts of atmospheric NO2 pollution on cause-specific mortality of different diseases in exposed population in Guangzhou[J].China Environmental Science,2022,42(8):3950-3956. |
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| Authors: | CAI Dong-jie YANG Jun HUANG Lin CHEN Su-juan ZHAO Wen-long DONG Hang LIN Guo-zhen WANG Bo-guang |
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| Affiliation: | 1. Institute for Environmental and Climate Research, Jinan University, Guangzhou 511443, China;2. School of Public Health, Guangzhou Medical University, Guangzhou 511436;3. Guangzhou Center for Disease Control and Prevention, Guangzhou 510440;4. Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Guangzhou 511443, China;5. JNU-QUT Joint Laboratory for Air Quality Science and Management, Jinan University, Guangzhou 511443, China |
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| Abstract: | Atmospheric NO2, a major gaseous pollutant, has received increasing attentions due to its high health risk, especially to human cardiopulmonary function. However, current assessments of the health effects of NO2 mainly focused on one single disease. In this study, the generalized additive model (GAM) was used to evaluate impacts of atmospheric NO2 pollution on cause-specific mortality (Relative risk, RR) in exposed population in Guangzhou during 2011~2015, as well as its cumulative lag effects2. Furthermore, the stratified analysis was performed in the cold season (November through April) and the warm season (May to October). The results show that effects of NO2 were observed to be rapid and transient, usually lasting for four days. In lag 0~4 days when the NO2 increased by 10μg/m3, the number of non-accidental deaths increased by 2.18% (RR=1.0218; 95% CI:1.0167, 1.0270) in the full year, and 2.6% (RR=1.0260; 95% CI:1.0191, 1.0328) in the cold season and 0.57% (RR=1.0057; 95% CI:0.9952, 1.0163) in the warm season. The difference in the NO2-induced mortality risks between cold and warm seasons was statistically significant (P=0.002). Among different diseases, NO2 pollution showed the greatest influence on chronic obstructive pulmonary disease. Therefore, atmospheric NO2 pollution is still an important risk to the residents in Guangzhou. And it is necessary to strengthen the control and management of NO2 emissions and implement the early warning of NO2 pollution to protect the public health, particularly during the cold season. |
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| Keywords: | NO2 mortality health risk GAM seasonal effect |
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