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甲壳低聚糖对小鼠肠道正常菌群的影响
引用本文:任林,陈超群,等.甲壳低聚糖对小鼠肠道正常菌群的影响[J].南华大学学报(医学版),2001,29(1):4-5,21.
作者姓名:任林  陈超群
作者单位:南华大学 医学部
基金项目:湖南省教委资助课题 !(98B10 3 )
摘    要:目的:观察甲壳低聚糖对小鼠肠肠道菌群的影响。方法:取昆明种小鼠20只,随机分为观察和对照组,分别用甲壳低聚糖600mg(kg.d)和等体积的生理盐水灌胃,连续7d,而后检测两组肠道菌群的变化。结果:观察组双歧杆菌数量比对照组明显增多(P<0.05),乳杆菌数量在两组间无明显差异,观察组大肠杆菌、肠球菌数量较对照组有减少趋势。结论:甲壳低聚糖具有调节小鼠肠道菌群及促进双歧杆菌增殖功能。

关 键 词:甲壳低聚糖  肠道菌群  小鼠
文章编号:1000-2510(2001)01-0004-02

Effect of Oligo-chitosan on Normal Intestinal Flora in Mice
REN Lin,CHEN Chao-qun,LI Bang-liang,et al.Effect of Oligo-chitosan on Normal Intestinal Flora in Mice[J].Journal of Nanhua University(Medical Edition),2001,29(1):4-5,21.
Authors:REN Lin  CHEN Chao-qun  LI Bang-liang  et al
Abstract:Objective: To investigate the effect of olig o-chitosan on nor mal intestinal flora in mice. Methods: Twenty mice were divided randomly into an observed group and a control group. The mice in the observed group we re administered (ig) oligo-chitosan at a dose of 600 mg/(kg*d) for seven da ys. The control group were received the same volume of normal saline for seven d ays. After seven days the levels of intestinal flora were measured. Resul ts: The amount of Bifidobacteria in the observed group obviously increase d as compared with that in the control group ( P<0.05), but the number of La ctobacillus had no significant change. Conclusion: It was indicated that olig o-chitosan could adjust the intestinal flora and could stimulate the proliferat ion of Bifidobacterium in mice efficiently.
Keywords:oligo-chitosan  intestinal  flora  mice
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