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抗肿瘤药物新靶点与新药研究
引用本文:车文军,李志裕,尤启冬.抗肿瘤药物新靶点与新药研究[J].药学进展,2007,31(6):247-253.
作者姓名:车文军  李志裕  尤启冬
作者单位:中国药科大学药物化学教研室,江苏,南京,210009
摘    要:抗肿瘤药物新靶点包括蛋白激酶、细胞周期和凋亡调节基因、蛋白法尼基转移酶、组蛋白去乙酰化酶和端粒酶。综述这些靶点及其相应药物近年来的研究进展。

关 键 词:肿瘤  抗肿瘤药物  靶点
文章编号:1001-5094(2007)06-0247-07
收稿时间:2007-03-21
修稿时间:2007-03-21

Current Targets for Anticancer Drug Discovery and the Related Drugs
CHE Wen-jun,LI Zhi-yu,YOU Qi-dong.Current Targets for Anticancer Drug Discovery and the Related Drugs[J].Progress in Pharmaceutical Sciences,2007,31(6):247-253.
Authors:CHE Wen-jun  LI Zhi-yu  YOU Qi-dong
Affiliation:Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China
Abstract:This review presents a comprehensive summary and discussion on the most important targets currently attracting a great deal of interest in contemporary anticancer drug design and discovery, including protein kinases, the cell cycle regulators, apoptosis modulators, FTase, histone deacetylase and telomerase.
Keywords:Turnout  Anticancer drug  Target
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