Some trends in medical populations genetics |
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| Authors: | J Feingold J L Serre P Carnevale |
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| Affiliation: | (1) Unité de Recherches de Génétique Epidémiologique, INSERM U. 155, Château de Longchamp, Bois de Boulogne, F-75016 Paris, (France);(2) Université Pierre et Marie Curie, Paris, (France);(3) Antenne ORSTOM, Bobo-Dioulasso, (Burkina Faso) |
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| Abstract: | Summary Five topics concerning medical population genetics have been selected for discussion: in the field of population cytogenetics, the frequency of chromosomal aberrations and the roles of mutation and selection in the maintenance of balanced rearrangements are studied; the long term genetic effects of treatment and prevention of genetic diseases are reviewed; the relationships between malaria and the sickle-cell trait are discussed; some recent works concerning human DNA polymorphisms in the field of population, genetics are presented, and finally, some methods of genetic epidemiology are described. |
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| Keywords: | Cytogenetics chromosomal aberrations genetic diseases malaria sickle-cell trait DNA polymorphisms genetic epidemiology |
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