| 人参皂苷Re的药理作用研究进展 |
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| 引用本文： | 韦豪华,张红玲,李兴太.人参皂苷Re的药理作用研究进展[J].大连民族学院学报,2018,20(1):21-26. |
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| 作者姓名： | 韦豪华 张红玲 李兴太 |
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| 作者单位： | 大连民族大学 生命科学学院,辽宁 大连 116605 |
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| 基金项目： | 辽宁省自然科学基金项目(201602192) |
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| 摘 要： | 为了使人参皂苷Re(Ginsenoside Re,GS-Re)在新药研究开发方面得到更深入的探讨,通过整理近十年的相关文献,对GS-Re的保护心血管系统、中枢神经系统、降血糖以及抗休克、抗血小板聚集等多种药效作用及药动学进行了综述。提出未来可考虑采用成酯的修饰方法对其结构内部的羟基官能团进行化学修饰,进而改变或加强GS-Re原有的理化性质。
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| 关 键 词： | 人参皂苷Re 药理作用 代谢研究 |
Research Progress in Pharmacological Activities of Ginsenoside Re |
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| WEI Hao-hua,ZHANG Hong-ling,LI Xing-tai.Research Progress in Pharmacological Activities of Ginsenoside Re[J].Journal of Dalian Nationalities University,2018,20(1):21-26. |
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| Authors: | WEI Hao-hua ZHANG Hong-ling LI Xing-tai |
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| Affiliation: | School of Life Science, Dalian Minzu University, Dalian Liaoning 116605, China |
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| Abstract: | In order to make deeper discussion on Ginsenoside Re (GS-Re) in research and development of new drugs, pharmacodynamic effects and pharmacokinetics of the protection of GS-Re on cardiovascular system and central nervous system, hypoglycemic, anti-shock, anti-platelet aggregation were reviewed by sorting out the relevant literatures in recent 10 years. It is proposed that the esterification chemically modifying the hydroxyl functional groups in the structure may be considered in the future so as to change or enhance the original physical and chemical properties of GS-Re. |
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| Keywords: | Ginsenoside Re pharmacological activities metabolism research |
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