| Minisci自由基取代反应最新研究进展 |
| |
| 作者单位： | ;1.河南牧业经济学院基础部 |
| |
| 摘 要： | Minisci反应是指亲核性的碳中心自由基与缺电子的底物分子发生反应,生成新的碳碳键的自由基取代反应,尤其适用于芳环或芳香杂环.该反应最早由F.Minisci在1970年首次发表.经典的Minisci反应是叔丁基甲酸在硝酸银以及过硫酸钾催化与吡啶环偶联得到吡啶取代物.介绍了Minisci反应的主要内容以及反应机理,并综述了该反应的最新研究进展,展望了此类反应今后发展趋势及应用前景.
|
| 关 键 词： | Minisci反应 自由基取代 研究进展 |
Recent Progress in a Radical Substitution of Minisci Reaction |
| |
| Affiliation: | ,Basic Research Department,Henan University of Animal Husbandry and Economy |
| |
| Abstract: | The Minisci reaction is a named reaction in organic chemistry.It's a radical substitution to an aromatic compound,in particular to a heteroaromatic base,that introduces an alkyl group.The reaction was published about in 1970 by F.Minisci.A typical reaction is that between pyridine and pivalic acid to 2-tert-butylpyridine with silver nitrate,sulfuric acid and ammonium persulfate.In the report,we introduce the reaction mechanism of Minisci reaction and summarize the latest research progress of the reaction. |
| |
| Keywords: | Minisci reaction radical substitution reaction research progress |
| 本文献已被 CNKI 等数据库收录！ |
|
