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Sequences and polymorphisms of exons 3 and 4 in porcine UCP2 gene
Authors:FANG Meiying  LIU Chousheng  ZHAO Xingbo  LI Ning  WU Changxin
Abstract:Uncoupling proteins are mitochondrial membrane transporters, which regulate metabolic pathways of energy balance, and are associated with biological traits of animal body weight, resting metabolic rates and energy conversion. In this study, a region of the exons 3 and 4 of pig UCP2 gene was cloned and analyzed, and a new single nucleotide polymorphic site was detected by PCR-SSCP in five pig breeds. This newfound polymorphism results from a T to G substitution at the position of nucleotide 272, which is located in intron3.
Keywords:pig  uncoupling proteins  PCR-SSCP
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