129例溃疡性结肠炎患者维医异常体液分型的量化诊断入选项专家咨询研究

 为了建立溃疡性结肠炎维医异常体液分型诊断标准，以非疾病诊断临床相关信息为依据，对诊断明确的129例溃疡性结肠炎患者进行量化诊断入选项专家咨询研究。对入选的证候要素进行多分类Logistic回归分析、共线性诊断及主成分分析，使用主成分改进的多分类Logistic回归分析方法确立各证候要素对证候的贡献度，根据OR值区分溃疡性结肠炎各异常体液型主症、次症。研究结果显示，溃疡性结肠炎异常黑胆质型主症为：口干不欲饮，舌苔晦暗，多梦、噩梦，小便青色，口味苦涩，唇色紫暗，舌质青紫；次症为：心神不宁，皮肤粗、凉。溃疡性结肠炎异常血液质型主症为：睡眠尚少，脉象粗、有力，结膜发红，舌质色深；次症为：口味甘苦，皮肤较热。溃疡性结肠炎异常粘液质型主症为：口黏，睡眠差，烦躁，皮肤凉、湿；次症为：面色发白，口淡无味，尿量较多，小便清长。溃疡性结肠炎异常胆液质型主症为：皮肤热，口干口渴，脉象细、浮，心急易怒，人面发黄，结膜微黄，唇色苍白，小便黄赤；次症为：舌体瘦、薄，口苦。经过对量化诊断入选项专家咨询所得到的临床信息的统计分析，认为研究结果与临床实际比较符合，可靠性高。由此得出结论：溃疡性结肠炎维医异常体液分型诊断标准的建立为开展溃疡性结肠炎维医临床疗效标准奠定了基础，该标准的建立也为方法学提供了参考。

Screening of Quantitative Diagnosis Indices of Typing Abnormal Hilit Syndrome in Uighur Medicine Using Delphi Method with 129 Cases of Ulcerative Colitis

To set up abnormal hilit typing quantitative diagnostic criteria of Uighur medicine for the Ulcerative colitis patients, based on the free disease clinical diagnostic information, 129 Ulcerative colitis patients were selected in the study of quantifying diagnosis specialist counseling. Selected factors were analyzed by the modified multi-categorization logistic regression analysis to determine the dedication degree and the main and subsequent symptoms of the symptom-complex factors of the abnormal hilit of Ulcerative colitis through the OR values. As the result, the meaningful symptoms were found in all the abnormal hilit syndromes according to the OR values. It is shown that the chief symptoms of the abnormal savda type Ulcerative colitis include dry mouth without desire to drink, dark and gloomy fur, dreaminess, nightmare, pale urine, bitter taste, dark purple lips, cyanotic tongue quality. Subsequent symptoms include not peaceful in mind, rough and cool skin. The chief symptoms of the abnormal kan type Ulcerative colitis include sleepless, thick、strong pulse, reddish conjunctiva, dark red tongue quality. Subsequent symptoms include bitter sweet taste, hot skin. The chief symptoms of abnormal balgham type Ulcerative colitis include sticky mouth, poor quality of sleep, fretful, cool and moist skin. Subsequent symptoms include whitish complexion, metallic taste (tasteless), increased urine volume, thin and pale urine. The chief symptoms of abnormal sapra type Ulcerative colitis include hot skin, dry mouth, thready, floating pulse, irritability, yellowish conjunctiva, yellowish complexion, pale lips, deep colored urine. Subsequent symptoms include thin tongue and bitter mouth. The features of excess syndromes of the four abnormal hilit syndromes on Ulcerative colitis identified by the Delphi method are in line with clinical observations. The establishment of the standards would provide a ground for developing the clinical effect standards for the traditional Uighur medicine and at the same time, a methodological reference for the establishment of the related standards.