| Discussion on Improvement of Toxicological Pathology Study |
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| 作者姓名： | Ren Jin |
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| 作者单位： | Shanghai Institute of Materia Medica，Shanghai Institutes for Biological Sciences，CAS，Shanghai 200031 |
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| 摘 要： | Toxicological pathology plays a key role in drug safety assessment. To enhance the research level of toxicological pathology, the following studies should be carried out urgently: setting up a standard operation procedure (SOP) for toxicological pathology assessment; emphasizing on immunotoxicology evaluation; adopting a new experiment model of replacement, featuring high speed and reliability; introducing new techniques and new models in toxicological mechanism research; and establishing a new appraisal system to screen innovative drug and rapid and high precision methods for early security assessment, detection and measurement.
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| 关 键 词： | 毒物病理学 药物安全评估 标准作业程序 免疫毒物学 |
Discussion on Improvement of Toxicological Pathology Study |
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| Ren Jin.Discussion on Improvement of Toxicological Pathology Study[J].Science Foundation in China,2003,11(1):31-34. |
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| Authors: | RenJin |
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| Affiliation: | ShanghaiInstituteofMateriaMedico,ShanghaiInstitutesforBiologicalSciences,CAS,Shanghai200031 |
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| Abstract: | Toxicological pathology plays a key role in drug safety assessment. To enhance the research level of toxicological pathology, the following studies should be carried out urgently: setting up a standard operation procedure (SOP) for toxicological pathology assessment; emphasizing on immunotoxicology evaluation; adopting a new experiment model of replacement, featuring high speed and reliability; introducing new techniques and new models in toxicological mechanism research; and establishing a new appraisal system to screen innovative drug and rapid and high precision methods for early security assessment, detection and measurement. |
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| Keywords: | drag safety assessment toxicological pathology immunotoxicology evaluation short-term replacement model highthroughput toxicology |
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