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石南藤中木脂素和新木脂素成分的研究
引用本文:段书涛,张鹏,俞培忠.石南藤中木脂素和新木脂素成分的研究[J].中国中药杂志,2010,35(2):180-182.
作者姓名:段书涛  张鹏  俞培忠
作者单位:复旦大学,药学院,天然药物化学教研室,上海,200032
摘    要:目的:对石南藤的化学成分进行研究.方法:采用各种色谱技术进行分离纯化,并利用理化常数和波谱数据鉴定化合物结构.结果:从石南藤50%乙醇提取物的二氯甲烷萃取部位分离并鉴定了9个化合物,其中包括1个木脂素(-)-gal-belgin(1)和8个新木脂素:玉兰脂B(2),山蒟素D(3),(+)-licarin A(4),海风藤酮(5),南藤素(6),山蒟素C(7),山蒟素B(8),(+)-burchellin(9).结论:化合物1,3,4,8,9为首次从该植物中分离得到.

关 键 词:石南藤  化学成分  木脂素  新木脂素
收稿时间:2009/6/26 0:00:00

Neolignans and lignan from Piper wallichii
DUAN Shutao,ZHANG Peng and YU Peizhong.Neolignans and lignan from Piper wallichii[J].China Journal of Chinese Materia Medica,2010,35(2):180-182.
Authors:DUAN Shutao  ZHANG Peng and YU Peizhong
Affiliation:Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University, Shanghai 200032, China;Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University, Shanghai 200032, China;Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University, Shanghai 200032, China
Abstract:To investigate the chemical constituents of the aerial part of Piper wallichii. Nine compounds were isolated by various chromatographic techniques and the structures were elucidated by their physicochemical properties and the spectral data analysis. Nine compounds were identified as one lignan (-)-galbelgin ( 1 ) and eight neolignans: denudatin B ( 2 ), hancinone D ( 3 ), (+)-licarin A ( 4 ), kadsurenone ( 5 ), wallichinine ( 6 ), hancinone C ( 7 ), hancinone B ( 8 ), (+)-burchellin ( 9 ). Compounds 1, 3, 4, 8, 9 were isolated from this plant for the first time.
Keywords:Piper wallichii  chemical constituents  lignan  neolignan
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