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慢性乙型肝炎患者远期生存质量研究
引用本文:巫贵成,周卫平,赵有蓉,郭树华,王志毅,邹淑碧,张全海,任红,黄爱龙,张定凤.慢性乙型肝炎患者远期生存质量研究[J].中华肝脏病杂志,2003,11(5):275-277.
作者姓名:巫贵成  周卫平  赵有蓉  郭树华  王志毅  邹淑碧  张全海  任红  黄爱龙  张定凤
作者单位:1. 重庆三峡中心医院消化科
2. 400010,重庆医科大学病毒性肝炎研究所
摘    要:目的 对慢性乙型肝炎患者远期生存质量进行研究,为其预后判断,药物疗效的分析及药品经济学评估提供依据。 方法 采用补充修订的SF-36健康相关生存质量量表调查101例6~l 8年前经肝穿活组织检查诊断的慢性乙型肝炎和105例门诊体检的普通人群。 结果 慢性乙型肝炎患者在生理机能、生理职能、总体健康、精神健康、肝病特有症状5个方面的远期生存质量低于普通人群,差异有显著性(μ≥2.10,P<0.05)。 结论 慢性乙型肝炎患者远期生存质量差。

关 键 词:肝炎  乙型  慢性  患者  生存质量  远期
修稿时间:2002年4月27日

Long-term health-related quality of life in chronic hepatitis B patients
WU Gui-cheng,ZHOU Wei-ping,ZHAO You-rong,GUO Shu-hua,WANG Zhi-yi,ZOU Shu-bi,ZHANG Quan-hai,REN Hong,Huang Ai-long,ZHANG Ding-feng. Institute for Viral Hepatitis,Chongqing University of Medical Sciences,Chongqing ,China.Long-term health-related quality of life in chronic hepatitis B patients[J].Chinese Journal of Hepatology,2003,11(5):275-277.
Authors:WU Gui-cheng  ZHOU Wei-ping  ZHAO You-rong  GUO Shu-hua  WANG Zhi-yi  ZOU Shu-bi  ZHANG Quan-hai  REN Hong  Huang Ai-long  ZHANG Ding-feng Institute for Viral Hepatitis  Chongqing University of Medical Sciences  Chongqing  China
Affiliation:Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Chongqing 400010, China.
Abstract:OBJECTIVE: To evaluate their long-term outcome and the efficacy and economic significance of antiviral drugs by investigating the long-term health-related quality of life (HQL) in chronic hepatitis B (CHB) patients. METHODS: The HQL of 101 CHB patients with biopsy-proven 6 to 18 years ago and 105 persons of general population as control was studied with revised SF-36 questionnaire. RESULTS: The HQL in CHB patients was lower than that in general population in physical functioning, role physical, general health, mental health, and specific symptoms (mu > or = 2.10, P<0.05). CONCLUSIONS: The long-term HQL in chronic hepatitis B patients is poor.
Keywords:Chronic hepatitis B  Patients  Long-term quality of life
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