围手术期心理干预对前列腺癌去势治疗患者心理状况及生活质量的影响

目的探讨围手术期心理干预对前列腺癌去势治疗患者心理状况及生活质量的影响。方法选择2005年1月-2011年12月间在我院泌尿外科行去势手术治疗的前列腺癌患者90例,随机分为心理干预组和对照组各45例,干预组患者除接受常规手术、药物治疗及护理外,予以围手术期心理干预;对照组接受常规的手术、药物治疗及护理。采用欧洲癌症研究和治疗协作组生活质量核心问卷(QLQ-C30),焦虑自评量表(SAS)及抑郁自评量表(SDS),由专职护士分别于干预前、术后7天及1个月(门诊复查时)与患者进行访谈,填写问卷进行评定。结果术后7天干预组患者的整体生活质量、角色功能、情感功能及认知功能的评分均高于对照组(t=2.45,P0.01;t=2.39,2.08,2.51;P0.05),而SAS及SDS评分则明显低于对照组(t=2.57,2.44;P0.01)。结论围手术期心理干预能改善前列腺癌去势治疗患者的心理状况,减轻焦虑抑郁情绪,提高生活质量。

The Effect of Psychological Interventions on Mental Status and Quality of Life for Patients with Prostate Cancer after Androgen Deprivation Therapy in Peri Operative Period

Objective To evaluate the impact of psychological interventions on mental status and quality of life for patients who suf- fered from prostate cancer after androgen deprivation therapy in peri operative period. Methods A retrospective review was performed in 90 patients who admitted to our hospital and received androgen deprivation therapy during January 2005 and December 2011. The pa- tients were randomized into research and control group. Each group contained 45 cases. The study group received regular operation, medicine and psychological interventions in perioperative period. The control group received the same scheme but for psychological inter- ventions. We investigated the European Organization for Research and Treatment of Cancer Core Questionnaire （ EORTC QLQ - c30）, Self-rating Anxiety Scale（SAS） and Self-rating Depression Scale（SDS） before intervention, 7 days and one month after operation. Re- sults The study group acquired higher scores in global quality of life （ t = 2. 45, P 〈 0.01 ）, role function （ t = 2. 39, P 〈 0.05 ）, emo- tional function（ t = 2. 08, P 〈 0.05 ） and cognitive function （t = 2. 51, P 〈 0.05 ）, but SAS（ t = 2. 57, P 〈 0.01 ） and SDS （ t = 2. 57, P 〈 0.01 ）were lower than those in control group. Conclusion Psychological interventions in peri operative period can improve health status of patients with prostate cancer after androgen deprivation therapy, reduce anxiety and depression, and improve their quality of life.