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滇黄芩化学成分的分离与鉴定
引用本文:肖丽和,王红燕,宋少江,张广平,宋海秀,徐绥绪.滇黄芩化学成分的分离与鉴定[J].沈阳药科大学学报,2003,20(3):181-183,193.
作者姓名:肖丽和  王红燕  宋少江  张广平  宋海秀  徐绥绪
作者单位:沈阳药科大学中药学院,辽宁,沈阳,110016
基金项目:国家自然科学基金资助项目 ( 30 0 70 919)
摘    要:目的研究滇黄芩 (ScutellariaamoenaC .H .Wright)化学成分。 方法利用各种色谱技术进行分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果分离得到 8个化合物 ,分别鉴定为 :5 ,7 二羟基 6 甲氧基二氢黄酮 (dihydrooroxylinA ,Ⅰ )、5 ,7,4′ 三羟基 8 甲氧基黄酮 ( 5 ,7,4′ trihydroxy 8 methoxyflavone ,Ⅱ )、千层纸素A(oroxylinA ,Ⅲ )、汉黄芩素 (wogonin ,Ⅳ )、白杨素 (chrysin ,Ⅴ )、黄芩素 (baicalein ,Ⅵ )、去甲汉黄芩素 (norwogonine ,Ⅶ )、( 2S) 5 ,7,2′ ,6′ 四羟基二氢黄酮 ( 2S) 5 ,7,2′ ,6′ tetrahydroxyflavanone ,Ⅷ ]。 结论化合物Ⅰ、Ⅱ为该植物中首次分得

关 键 词:滇黄芩  化学成分  5  7-二羟基-6-甲氧基二氢黄酮  5  7  4′-三羟基-8-甲氧基黄酮
文章编号:1006-2858(2003)03-0181-03

Isolation and identification of the chemical constituents of Roots of Scutellaria amoena C.H.Wright
XIAO Li he,WANG Hong yan,SONG Shao jiang,ZHANG Guang ping,SONG Hai xiu,XU Sui xu.Isolation and identification of the chemical constituents of Roots of Scutellaria amoena C.H.Wright[J].Journal of Shenyang Pharmaceutical University,2003,20(3):181-183,193.
Authors:XIAO Li he  WANG Hong yan  SONG Shao jiang  ZHANG Guang ping  SONG Hai xiu  XU Sui xu
Abstract:Objective To study the chemical composition of roots of Scutellaria amoena C.H.Wright.Methods Various chromatographic techniques were used to separate and purify the constituents.Their structures were determined by chemical evidences and spectral analysis.Results Eight compounds were isolated and purified,their structures were identified as dihydrooroxylin A(Ⅰ),5,7,4′ trihydroxy 8 methoxyflavone(Ⅱ),oroxylin A(Ⅲ),wogonine(Ⅳ),chrysin(Ⅴ),baicalein(Ⅵ),norwogonine(Ⅶ),(2 S ) 5,7,2′,6′ tetrahydroxyflavanone(Ⅷ).Conclusion CompoundⅠandⅡare separated from Scutellaria amoena C.H.Wright for the first time.
Keywords:Scutellaria amoenaC  H  Wright  chemical constituents  dihydrooroxylin A  5  7  4′trihydroxy  8  methoxyflavone
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