| 中度高原地区正常及妊高征孕妇超氧化物歧化酶和丙二醛水平的初步研究 |
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| 引用本文： | 李娟,毛炎红,阿祥仁.中度高原地区正常及妊高征孕妇超氧化物歧化酶和丙二醛水平的初步研究[J].高原医学杂志,1995(2). |
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| 作者姓名： | 李娟 毛炎红 阿祥仁 |
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| 作者单位： | 西宁市第一人民医院妇产科，青海省人民医院老年病研究室 |
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| 摘 要： | 本文测定了未孕妇女、正常孕妇和妊高征孕妇的超氧化物歧化酶（ＳＯＤ），丙二醛（ＭＤＡ）和维生素Ｅ（ＶＥ）水平。结果为正常孕妇ＳＯＤ低于未孕妇女，而ＭＤＡ和ＶＥ高子未孕妇女（Ｐ均＜０．０１），提示孕妇抗氧化能力可能增强。妊高征孕妇与正常孕妇相比，ＳＯＤ、ＶＥ更低（Ｐ＜０．０１），而ＭＤＡ则更高（Ｐ＜０．０５），而且妊高征孕妇的ＭＤＡ与ＳＯＤ、ＭＤＡ与ＶＥ呈负相关（ｒ＝－０．９５６，－０．７０４８、Ｐ＜０．０５），提示可能有脂质过氧化反应的增强和氧化能力下降，为妊高征的急性动脉硬化提供了条件。
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| 关 键 词： | 正常孕妇，妊高征，超氧化物歧化酶，丙二醛，中度高原 |
A STUDY ON SOD AND MDA DURING PREGNANCY WITH AND WITHOUT GESTIONAL
HYPERTENSION AT HIGH ALTITUDE |
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| Li Juan,et al.A STUDY ON SOD AND MDA DURING PREGNANCY WITH AND WITHOUT GESTIONAL
HYPERTENSION AT HIGH ALTITUDE[J].Journal of High Altitude Medicine,1995(2). |
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| Authors: | Li Juan |
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| Affiliation: | The First Hospital of
Xining |
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| Abstract: | uperoxide dismutase(SOD),Vitamin Eand malondialdehyde
(MDA)Were investigated innon-Peregnant(NONP),normal
pregnant(NORP),abnormal pregnant(gestional hroertension)(ABNP)women
at 2 260m high altitude. The results showed that SOD in NORP was
lower thanNONP,but their ,MDA and vitamin E were higher than
NONP.SOD and vitamin E in ABRP were lower(P<0.01),but MDA was
higber(P<0.05)thanNOKP.IN ABRP MDA and SOD,MDA and vitamin E showed a
negative correlation(r=n0.956,-0.7048,P<0.05,respectlvely).The
results suggested that the antioxidation in NORPmight be increased,in
ABRP the lipid peroxidation might be increased but antioxidation
de-creased.The results indicated that the changes of SOD and MDA at
high altitude might relatewith acute arteriosclerosis in the pregnant
women with gestional hypertension,for which futherstudy is needed. |
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| Keywords: | pregnancy gestational hypertantion malondialdehyde superoxide dismutase high altitude |
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