| 氨氯地平与尼群地平治疗高血压的多中心平行对照研究 |
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| 引用本文： | 王宪衍,龚兰生,郭冀珍,王孝铭,刘玉慧,叶绪英,张国元,杨培林.氨氯地平与尼群地平治疗高血压的多中心平行对照研究[J].高血压杂志,1994(2). |
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| 作者姓名： | 王宪衍 龚兰生 郭冀珍 王孝铭 刘玉慧 叶绪英 张国元 杨培林 |
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| 作者单位： | 上海第二医科大学附属瑞金医院，上海市高血压研究所!200025，上海第二医科大学附属瑞金医院，上海市高血压研究所!200025，上海第二医科大学附属瑞金医院，上海市高血压研究所!200025，上海第二医科大学附属瑞金医院，上海市高血压研究所!200025，大连医学院附属第二医院，大连医学 |
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| 摘 要： | 采用多中心、随机、单盲、组间、平行对照的方法对488例原发性高血压患者进行氨氯地平或尼群地平4周治疗观察，显示氨氯地平的降压有效率为90．4％，较尼群地平显著为高。不良反应较少，安全性好。每日只需服药1次，剂量5～10mg，方便病人。
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| 关 键 词： | 氨氯地平 尼群地平 原发性高血压 钙离子拮抗剂 |
Multicenter Parallel Study of Amlodipine Versus Nitrendipine in Treatment Essential Hypertension |
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| Wang Xianyan, Gong Lanshcng, Guo Jizbenl, Wang Xiaoming, Liu Yuhui, Ye Xuying, Zhang Guoyuan, Yang Peilin.Multicenter Parallel Study of Amlodipine Versus Nitrendipine in Treatment Essential Hypertension[J].Chinese Journal of Hypertension,1994(2). |
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| Authors: | Wang Xianyan Gong Lanshcng Guo Jizbenl Wang Xiaoming Liu Yuhui Ye Xuying Zhang Guoyuan Yang Peilin |
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| Abstract: | In a multicenter, randomized l sing1e blind and para11e1 study, 488 patients with essential hypertension were completed 4 week t1'eatment with amlodipine 0r nitrendipine. It showed that the response rates of amlodipine were 90. 4% and it was higher than that of nitrendipine. Its adverse effets were fewer than those of nitrendipine. In conclusi0n,amlodipine is a safe and effective antihypertensive agent. Its once daily (5~ 1Omg) dosage makes it very c0nvenient for patients. |
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| Keywords: | amlodipine nitrendipine essential hypertension I calcium antagonist |
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