| 唑来膦酸联合局部放疗治疗恶性肿瘤骨转移疼痛临床疗效观察 |
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| 引用本文： | 何敬波,张凌云,易铁男,谢丛华.唑来膦酸联合局部放疗治疗恶性肿瘤骨转移疼痛临床疗效观察[J].江苏临床医学杂志,2012(3):93-94. |
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| 作者姓名： | 何敬波 张凌云 易铁男 谢丛华 |
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| 作者单位： | 襄樊学院医学院襄阳市中心医院肿瘤1科,湖北襄阳441021 |
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| 摘 要： | 目的观察唑来膦酸联合局部放疗治疗恶性肿瘤骨转移引起的疼痛的临床疗效。方法 45例确诊为恶性肿瘤骨转移的患者应用唑来膦酸药物治疗,同时接受局部放射治疗。结果接受联合治疗的45例患者中,完全缓解（CR）12例（26.7%）,部分缓解（PR）20例44.4%,轻度缓解（MR）8例（17.8%）,无效（NR）5例（11.1%）;总缓解率（CR＋PR＋MR）为88.9%;均未发现严重的毒副作用。结论唑来膦酸联合局部放射治疗恶性肿瘤骨转移引起的疼痛临床应用安全、有效。
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| 关 键 词： | 唑来膦酸 放射治疗 骨转移 癌症 疼痛 |
Clinical efficacy of the combination of zoledronate and local radiotherapy in relieving the pains of patients with bone metastatis |
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| HE Jing-bo,ZHANG Lin-Yun,YI Tie-nan,XIE Cong-hua.Clinical efficacy of the combination of zoledronate and local radiotherapy in relieving the pains of patients with bone metastatis[J].Journal of Jiangsu Clinical Medicine,2012(3):93-94. |
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| Authors: | HE Jing-bo ZHANG Lin-Yun YI Tie-nan XIE Cong-hua |
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| Affiliation: | (Xiangyang Central Hospital of Xiangfang College,Xinagfan,Hubei,441021) |
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| Abstract: | Objective To observe the efficacy of zolendronate combined with local radio-therapy in relieving the pains of patients with bone metastatis.Methods Forty-five patients with bone metastatis pains were treated with zolendronate and local radiotherapy.Results Twelve pa-tients were relieved completely（CR）,20 partially（PR） and 8 mildly（MR）.The overall pain relief（CR＋PR＋MR） rate was 88.9%.No side effects were observed in these patients.Conclusion The treatment of zolendronate combined with local radiotherapy is safe and effective for patients with bone metastatis pains. |
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| Keywords: | zolendronate radiotherapy bone metastatis cancer pain |
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