新疆地区四肢长骨骨巨细胞瘤的外科治疗

  目的  回顾性分析长骨骨巨细胞瘤不同手术方法的临床疗效。  方法  回顾2007年1月至2012年6月收治四肢长骨骨巨细胞瘤37例，男性20例，女性17例；平均年龄为31.6（20~56）岁。分析假体置换手术和非假体置换手术对术后的复发、肢体功能，综合评定其影响；不同民族之间发病率，复发率的分析；上下肢的发病率，复发率的分析。  结果  本研究病例好发年龄为20~50岁，维吾尔族发病率较高，民族之间复发率差异无统计学意义（P>0.05）。  结论  骨巨细胞瘤好发年龄为20~50岁，维吾尔族发病率较汉族及其他民族高。下肢发病率及复发率均要高于上肢。切除后植骨或骨水泥填充、植骨内固定、瘤段切除人工关节置换均是骨巨细胞瘤的可靠治疗方法。 

Surgical treatment of giant-cell tumor of long extremity bones

  Objective   To analyze the clinical effect of different surgical methods on giant-cell tumor of bone (GCTB).  Methods   Between January 2007 and June 2012, 37 patients receiving treatment for GCTB were enrolled in this study. These patients included 20 males and 17 females whose ages ranged from 20 to 56 (average=31.6). The prosthesis replacement and nonprosthetic replacement operation on the postoperative recurrence, limb function, comprehensive evaluation of the curative effect, as well as morbidity and recurrence rate among different nations and in the upper and lower limbs of GCTB patients were analyzed.  Results   The predilection age of the cases ranged from 20 to 50 years old. The incidence was higher in the Uighur population of Xinjiang, China. However, the recurrence rate in ethnic difference was not statistically significant (P>0.05).  Conclusion   The predilection age of GCTB cases was 20~50 years old, with higher morbidity in Uighur than in Han and other ethnic groups. The morbidity and recurrence rate were higher in the lower limbs than in the upper limbs of patients. The scraping bone graft and bone cement filling, the internal fixation of the scraping bone graft, and the artificial joint replacement of tumor resection were all reliable modes of treatment.