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| Qi盐对正常及糖尿病模型大鼠血糖的影响 | |
| 引用本文： | 翁鸿博,张一鸣,李端,程能能,黄维蓉,佐藤稔,上田秀夫.Qi盐对正常及糖尿病模型大鼠血糖的影响[J].中国临床药学杂志,2004,13(4):196-198. |
| 作者姓名： | 翁鸿博 张一鸣 李端 程能能 黄维蓉 佐藤稔 上田秀夫 |
| 作者单位： | 1. 复旦大学药学院药理学教研室,上海,200032 2. 上海市医药学校药理教研室,上海,200032 3. 日本盐生命科学研究所 |
| 基金项目： | SupportedbyQipower,Inc.Tokyo,Japan |
| 摘 要： | 目的观察Qi盐对正常小鼠和糖尿病模型大鼠的降血糖作用.方法尾静脉注射四氧嘧啶制作大鼠糖尿病模型,连续灌胃给Qi盐14
d,葡萄糖氧化酶法测血糖.结果Qi盐1.6,0.8,0.4 g·kg-1对正常小鼠血糖及糖耐量均无明显影响,但0.8,0.4
g·kg-1可降低四氧嘧啶模型大鼠血糖,改善糖耐量.结论Qi盐对糖尿病模型大鼠有降血糖作用. |
| 关 键 词： | Qi盐 糖尿病 动物模型 大鼠 降血糖 |
Effect of Qi salt on blood glucose in normal mice and diabetic rats |
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| Abstract.Effect of Qi salt on blood glucose in normal mice and diabetic rats[J].Chinese Journal of Clinical Pharmacy,2004,13(4):196-198. | |
| Authors: | Abstract |
| Abstract: | AIM: To study hypoglycemic effects of Qi salt in normal mice and alloxan-induced diabetic rats.METHODS:The model of diabetic rats was prepared by injecting alloxan. Blood samples were collected from tail vein and blood glucose levels were measured with glucose oxidase method after oral administration Qi salt 14 d. Glucose tolerance test was performed. RESULTS: The blood glucose level and glucose tolerance did not be changed by Qi salt 1.6,glucose level was markedly reduced and glucose tolerance was also improved. CONCLUSION: Qi salt exerts significant antihyperglycemic effect in diabetic rats. |
| Keywords: | Qi salt blood glucose glucose tolerance |
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