127例外源性化脓性眼内炎病原体及药敏试验结果分析

目的：分析外源性化脓性眼内炎病原体及其对药物敏感性的变迁，为临床合理用药提供依据。方法：对127例(127眼)经临床诊断为化脓性眼内炎的前房水或玻璃体液标本进行涂片检查、细菌培养、真菌培养，对细菌培养阳性菌株进行药物敏感试验，然后对培养结果及药物敏感试验结果进行统计分析。结果：外源性化脓性眼内炎涂片阳性率为22．05％，细菌及真菌培养阳性率为42．52％。其主要致病菌为表皮葡萄球菌、枯草杆菌及铜绿假单孢杆菌。大多数细菌对环丙沙星敏感，对氯霉素、利福平、头孢唑琳耐药。结论：对化脓性眼内炎患者的前房水或玻璃体液进行涂片、培养及药物敏感试验有助于明确眼内炎的性质及指导临床用药的选择。

An analysis of bacteria culture in suppurative endophthalmitis

Objective:To study the changes in bacterial spectrum and drug sensitivity in the culture test of aqueous or vitreous specimens from the patients with suppurative endophthalmitis and to search sensitive antibiotic. Methods:Aqueous or vitreous specimens were taken from 127 eyes of 127 cases of clinically diagnosed suppurative endophthalmitis for spreading slice,bacterial and fugal culture,and drug sensitivity test. Results:The positive rate of spreading slice was 22 05% and culture positive rate was 42 52%.The main bacteria spectrum of suppurative endophthalmitis was Staphylococcus epidermidis and Pseudomonas aeraginosa.Most bacteria were sensitive to Ciprofloxacin and were resistant to Chloromycetin,Rifampine andCefazoline. Conclusions:The main bacteria spectrum of suppurative endophthalmitis is Staphylococcus epidermidis and Pseudomonas aeraginosa.Most bacteria are sensitive to Ciprofloxacin.