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尿微量白蛋白与冠状动脉病变程度的相关性分析
引用本文:吴镜,蔡琳,燕纯伯,王伟,唐炯,邓晓奇,余秀琼.尿微量白蛋白与冠状动脉病变程度的相关性分析[J].华西医学,2009(10):2609-2612.
作者姓名:吴镜  蔡琳  燕纯伯  王伟  唐炯  邓晓奇  余秀琼
作者单位:成都市第三人民医院心内科,四川成都610031
摘    要:目的:研究尿微量白蛋白与冠心病的相关性。方法:按冠状动脉造影诊断标准将116例患者分为冠心病组(82人)与非冠心病组(34人),测定晨尿白蛋白/肌酐浓度值(ACR),比较两组患者尿ACR并分析ACR与冠脉病变程度的相关性。结果:冠心病组ACR显著高于非冠心病组的;ACR与冠脉计分呈显著的直线正相关。结论:冠心病患者ACR水平升高,微量白蛋白尿与冠状动脉病变范围和程度密切相关,且对冠状动脉狭窄程度具有独立预测价值。

关 键 词:尿微量白蛋白  冠状动脉疾病  相关性分析

The Relationship between Microalbuminuria and Coronary Artery Disease
Affiliation:WU Jing,CAI Lin,YAN Chun-bo,et al.(the Department of Cardiology,the Third People's Hospital of Chengdu,Chengdu 610031,China )
Abstract:Objective:To investigate the relationship between microalbuminuria and coronary artery disease(CAD).Methods:According to the diagnostic standard of coronary artery angiography,116 patients were divided into CAD group (82 patients) and non-CAD group (34 patients).The albumin and creatinine concentrationratio ratio(ACR) in morning urine samples from patients of both groups was estimated and compared.The correlation of ACR to the extent of coronary lesions was analyzed.Results:ACR in the CAD group was significantly higher than that in non-CAD group.A distinctly linear positive correlation existed between ACR and the score of the coronary lesions.Conclusion:ACR increase in patients with CHD.Micoalbuminuria was associated with the severity of coronary lesions in patients with CHD and is an independent predictor of CAD.
Keywords:albuminuria  coronary disease  correlation
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