| ALA—PDT治疗男性尿道口尖锐湿疣的疗效观察 |
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| 引用本文： | 袁艳霞,徐春兴,田婷.ALA—PDT治疗男性尿道口尖锐湿疣的疗效观察[J].中国现代医生,2012,50(2):141-142. |
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| 作者姓名： | 袁艳霞 徐春兴 田婷 |
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| 作者单位： | 江苏省常州市第一人民医院皮肤性病科,江苏常州,213000 |
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| 摘 要： | 目的观察外用氨基酮戊酸光动力疗法（ALA—PDT）治疗男性尿道口尖锐湿疣的疗效和安全性。方法将72例男性尿道口尖锐湿疣患者随机分为ALA—PDT治疗组和CO2激光治疗对照组，每周治疗1次，不超过3次。末次治疗后1周进行疗效评价，随访12周观察皮疹复发情况及不良反应。结果末次治疗后1周，治疗组和对照组临床痊愈率均为100％（P〉0．05），治疗组复发率（11．1％）显著低于对照组（41．7％）（P〈0．01）。治疗组2例患者局部出现浅表糜烂，所有患者无瘢痕形成；对照组11例出现不同程度的瘢痕形成。结论外用ALA—PDT治疗男性尿道口尖锐湿疣治愈率高、复发率低、安全性好。
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| 关 键 词： | 5-氨基酮戊酸 光动力疗法 尖锐湿疣 尿道口 |
Clinical observation of ALA-PDT in the treatment of urethal condyloma acuminatum |
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| Authors: | YUAN Yanxia XU Chunxing TIAN Ting |
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| Affiliation: | Department of Dermatology and Venereology,the First People’s Hospital of Changzhou,Changzhou 213000,China |
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| Abstract: | Objective To investigate the clinical efficacy and safety of 5-aminolevuinic acid photodynamic therapy(ALA-PDT) in the treatment of urethal condyloma acuminatum.Methods Seventy-two male patients with urethal condyloma acuminatum were randomly divided into ALA-PDT group and CO2 laser group.The treatment was repeated weekly and no more than 3 times.All patients were followed up for 12 weeks.The therapeutic effect and safty were evaluated.Results The cure rate were 100% of two groups at 1 week after the last treatment,and the recurrent rate of ALA-PDT group(11.1%) was significantly lower than that of the control group(41.7%)(P<0.01).2 patients in treatment group had superficial erosion,11 patients in control group had scar.Conclusion ALA-PDT is an effective and safe therapy with lower recurrence for the treatment of urethal condyloma acuminatum. |
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| Keywords: | Aminolevuinic acid Photodynamic therapy Condyloma acuminatum Urethra |
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