| 银杏叶对小鼠海马神经元超微结构的影响及抗衰老作用 |
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| 引用本文： | 吴树亮,金连弘,肖辉,田波,李竹英,孟祥和.银杏叶对小鼠海马神经元超微结构的影响及抗衰老作用[J].中国局解手术学杂志,2002,11(4):346-348. |
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| 作者姓名： | 吴树亮 金连弘 肖辉 田波 李竹英 孟祥和 |
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| 作者单位： | [1]哈尔滨医科大学神经生物学教研室150001 [2]附属二院耳鼻喉科 |
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| 摘 要： | 目的 研究银杏叶提取物对小鼠海马神经元超微结构的影响及抗衰老作用。方法 取小鼠海马作实验材料，用定量体视学方法观察两组小鼠在不同时期海马神经元胞体，胞核，核仁等形态参数的变化，然后对结果用逐步回归的方法进行分析。结果 随着鼠龄的增加，细胞核体积逐渐减少。神经元损失较多，而银杏叶组上述变化较不明显。结论 银杏叶提取物可以影响小鼠海马神经元的超微结构，具有抗衰老作用。
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| 关 键 词： | 银杏叶 小鼠 海马 神经元 超微结构 抗衰老作用 |
| 修稿时间： | 2002年11月3日 |
Effects of gingkgo leaf on the ultrastructure of mouse hippocampal neuron and on consenescence |
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| Wu Shuliang,Jin Lianhong,Xiao Hui,et al..Effects of gingkgo leaf on the ultrastructure of mouse hippocampal neuron and on consenescence[J].Journal of Regional Anatomy and Operative Surgery,2002,11(4):346-348. |
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| Authors: | Wu Shuliang Jin Lianhong Xiao Hui |
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| Affiliation: | Wu Shuliang,Jin Lianhong,Xiao Hui,et al. Department of Newobiology,Harbin Medical University,Harbin 150001 |
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| Abstract: | Objective To study the effect of gingkgo leaf on the ultrastructure of hippocampal neuron in mouse and its anti-consenescence effect. Methods Using hippocampus of mouse as experimental materials, changes of morphological parameters of neuronal cell body, nuclei and nucleolus in different period in control and gingkgo leaf treated groups were observed by quantitative stereological method and the results were analyzed with gradual - regression method. Results With the incresing of the age of mouse, the volume of cell body and the number of neurons decreased . Conclusion The gingkgo leaf may affect the ultrastructure of mouse hippocampus and may delay consenescence. |
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| Keywords: | Mouse Gingkgo biloba Hippocampus neuronal ultrastructure Anti-consenescence |
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