| 氨氯地平联合特拉唑嗪降低残余尿量和尿潴留风险的疗效分析 |
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| 引用本文： | 杨春,李友龙,方建,张枭,刘海鹏,秦献辉,徐希平.氨氯地平联合特拉唑嗪降低残余尿量和尿潴留风险的疗效分析[J].中华男科学杂志,2009,15(5):441-444. |
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| 作者姓名： | 杨春 李友龙 方建 张枭 刘海鹏 秦献辉 徐希平 |
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| 作者单位： | 1. 安徽医科大学安徽省生物医学研究所,安徽,合肥,230032
2. 中国科学技术大学生命科学学院,安徽,合肥,230026 |
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| 摘 要： | 目的:探讨氨氯地平及氨氯地平联合特拉唑嗪改善男性下尿路症状(LUTS)合并高血压患者残余尿(PVR)的疗效。方法:360例男性BPH合并高血压患者进入随机双盲临床实验,随机进入特拉唑嗪(2 mg/d)、氨氯地平(5 mg/d)、联合用药组(特拉唑嗪2 mg/d+氨氯地平5 mg/d)3个治疗组,各120例,分别测定治疗4周前后的PVR值。应用非参检验及回归分析氨氯地平及联合用药的有效性。结果:对于男性LUTS合并高血压患者,氨氯地平(ΔPVR=6.8)、特拉唑嗪(ΔPVR=7.6)及联合用药(ΔPVR=8.8)均能能有效降低PVR(P均<0.01),但三者间疗效无明显差异。结论:氨氯地平单独或联合特拉唑嗪可以有效改善LUTS患者PVR,但效果与单用特拉唑嗪并无明显区别。
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| 关 键 词： | 残余尿 良性前列腺增生 高血压 氨氯地平 特拉唑嗪 |
Amlodipine Combined with Terazosin Reduces Postvoid Residual and the Risk of Acute Urinary Retention |
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| YANG Chun,LI You-long,FANG Jian,ZHANG Xiao,LIU Hai-peng,QIN Xian-hui,XU Xi-ping.Amlodipine Combined with Terazosin Reduces Postvoid Residual and the Risk of Acute Urinary Retention[J].National Journal of Andrology,2009,15(5):441-444. |
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| Authors: | YANG Chun LI You-long FANG Jian ZHANG Xiao LIU Hai-peng QIN Xian-hui XU Xi-ping |
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| Affiliation: | YANG Chun1,LI You-long1,FANG Jian1,ZHANG Xiao1,LIU Hai-peng2,QIN Xian-hui1,XU Xi-ping11.Anhui Provincial Institute of Biomedicine,Anhui Medical University,Hefei,Anhui 230032,China,2.School of Life Science,University of Science , Technology of China,Anhui 230026 |
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| Abstract: | Objective:This prospective randomized double-blinded clinical trial was designed to explore the effects of amlodipine and the combination of amlodipine with terazosin in improving postvoid residual(PVR) in patients with lower urinary tract symptoms(LUTS) and concomitant hypertension.Methods: We randomly divided 360 LUTS patients with concomitant hypertension into a 5 mg amlodipine group,a 2 mg terazosin group and a 5 mg amlodipine plus 2 mg terazosin group,and measured PVR at the baseline and 4 weeks after ... |
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| Keywords: | postvoid residual benign prostatic hyperplasia hypertension amlodipine terazosin |
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