| 围手术期胶质瘤患者细胞免疫功能的表达 |
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| 引用本文： | 郭世文,张晓东,何百祥,姜海涛,王拓,刘守勋.围手术期胶质瘤患者细胞免疫功能的表达[J].肿瘤防治研究,2003,30(1):51-52. |
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| 作者姓名： | 郭世文 张晓东 何百祥 姜海涛 王拓 刘守勋 |
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| 作者单位： | 710061,西安交通大学第一医院神经外科 |
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| 摘 要： | 目的 探讨围手术期胶质瘤患者细胞免疫功能的表达。方法 用免疫荧光技术检测 4 8例胶质瘤患者围手术期T淋巴细胞亚群和NK细胞百分率。结果 胶质瘤患者CD3、CD4 、CD8及CD4 /CD8比值均明显低于对照组 ;肿瘤切除术后细胞免疫功能有所恢复 ,但与术前比较无明显差异 ,且仍低于正常状态。结论 胶质瘤患者细胞免疫功能低下 ,且肿瘤切除术后其细胞免疫功能尚难很快恢复到正常状态 ,临床上应注意围手术期细胞免疫功能的保护。
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| 关 键 词： | 胶质瘤 细胞免疫 手术治疗 |
| 文章编号： | 1000-8578(2003)01-0051-02 |
| 收稿时间： | 2002-1-31 |
| 修稿时间： | 2002年1月31日 |
Changes of perioperation cellular immune function in patients with gliomas |
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| GUO SHi wen,ZHANG Xiao dong,HE Bai xiang,et al.Changes of perioperation cellular immune function in patients with gliomas[J].Cancer Research on Prevention and Treatment,2003,30(1):51-52. |
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| Authors: | GUO SHi wen ZHANG Xiao dong HE Bai xiang |
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| Affiliation: | GUO SHi wen,ZHANG Xiao dong,HE Bai xiang,et al Department of Neurosurgery,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China |
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| Abstract: | Objective The cellular immune function was investigated before and after operation in patients with glioma.Methods The positive percentage of T lymphocyte phenotype and NK cell were examined dynamically by method of direct immunofluorence. Results The percentage of CD 3 ?CD 4 ?CD 8 and the ratio of CD 4 /CD 8 in glioma patients were much lower than those of the controls. The cellular immune function increased slightly after tumor removal. But there was no significant difference betwee... |
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| Keywords: | Glioma Cellular imunity Surgery |
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