| 黑老虎果毒理实验及其对血脂的调节作用 |
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| 引用本文： | 李志春,孙健,封毅,卓少元,乐宁,尧金燕,龙兴.黑老虎果毒理实验及其对血脂的调节作用[J].食品科学,2011(1). |
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| 作者姓名： | 李志春 孙健 封毅 卓少元 乐宁 尧金燕 龙兴 |
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| 作者单位： | 广西农业科学院农产品加工研究所;广西作物遗传改良重点开放实验室;广西中医学院基础医学院;广西农业科学院园艺研究所; |
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| 基金项目： | 广西自然科学基金项目(2010GXNSFB013034;2010GXNSFC013010); 广西农业科学院博士启动基金项目(20090306) |
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| 摘 要： | 研究成熟黑老虎果的毒性及其对血脂的调节作用。对实验小鼠进行急性毒理实验,同时进行30d喂养实验,并观察小鼠血脂的变化。结果表明:雌雄小鼠经口最大耐受剂量(MTD)>20mL/kg(以体质量计),属无毒级;30d喂养实验各项观察指标正常,黑老虎果对小鼠的体质量、血液、脏器等均无显著影响;该果能明显降低小鼠血液中胆固醇水平。可以认为,成熟黑老虎果是值得开发的无毒且可调节血脂的珍稀野生水果。
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| 关 键 词： | 黑老虎果 毒性 血脂 调节 |
An Experimental Animal Investigation on Toxicity and Blood Lipid Modulating Effect of Kadsura coccinea Fruit |
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| LI Zhi-chun,SUN Jian,FENG Yi,ZHUO Shao-yuan,LE Ning,YAO Jin-yan,LONG Xing.An Experimental Animal Investigation on Toxicity and Blood Lipid Modulating Effect of Kadsura coccinea Fruit[J].Food Science,2011(1). |
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| Authors: | LI Zhi-chun SUN Jian FENG Yi ZHUO Shao-yuan LE Ning YAO Jin-yan LONG Xing |
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| Affiliation: | LI Zhi-chun1,2,SUN Jian1,FENG Yi3,ZHUO Shao-yuan3,LE Ning3,YAO Jin-yan4,LONG Xing4 (1.Institute of Agro-food Science & Technology,Guangxi Academy of Agricultural Sciences,Nanning 530007 China,2.Guangxi Crop Genetic Improvement Laboratory,Nanning 530007,China,3.Faculty of Preclinical Medicine,Guangxi Traditional Chinese Medical University,Nanning 530001 China,4.Horticultural Research Institute,China) |
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| Abstract: | The aim of this study was to investigate the toxicity and blood lipid modulating effect of ripe Kadsura conccinea fruit in vivo by maximal tolerance dose(MTD) test and 30-d feeding test in mice.Blood lipid changes in mice were analyzed during 30 days of Kadsura conccinea fruit feeding.The results showed MTD was >20 mL/kg for both male and female mice,indicating that Kadsura conccinea fruit was non-toxic.Kadsura conccinea fruit had significant effect on neither mouse weight nor viscera but could obviously re... |
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| Keywords: | Kadsura conccinea fruit toxicity blood lipids modulating |
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