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缬沙坦治疗心力衰竭合并肾功能不全30例疗效观察
引用本文:马景涛,徐芳.缬沙坦治疗心力衰竭合并肾功能不全30例疗效观察[J].实用心脑肺血管病杂志,2006,14(8):638-639.
作者姓名:马景涛  徐芳
作者单位:050011,河北省石家庄市,河北医科大学第四医院心血管内科
摘    要:目的观察缬沙坦对心力衰竭合并肾功能不全患者的疗效和安全性。方法30例伴有心力衰竭合并轻度肾功能不全的患者给予缬沙坦(80mg/d)和呋塞米(20mg/d)治疗4周,观察心功能分级、血肌酐的变化。结果4周后患者心力衰竭症状明显减轻,患者血肌酐水平明显下降(P〈0.01)。结论缬沙坦能有效控制心力衰竭患者的临床症状,安全地应用于心力衰竭合并轻度肾功能不全的患者,有效降低患者的血肌酐水平。

关 键 词:血管紧张素Ⅱ受体拮抗剂  心力衰竭  肾功能衰竭
文章编号:1008-5971(2006)08-0638-02
收稿时间:2006-04-06
修稿时间:2006年4月6日

Effects of Therapy with Valsartan in Patients with Chronic Heart Failure and Kidney Failure
MA Jing-tao,XU Fang.Effects of Therapy with Valsartan in Patients with Chronic Heart Failure and Kidney Failure[J].Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease,2006,14(8):638-639.
Authors:MA Jing-tao  XU Fang
Affiliation:Department of Cardiology,the Fourth Hospital of Hebei Medical University ,Hebei Province ,Shijiazhuang 050011, China
Abstract:Objective To observe the effect of therapy with valsartan in patients with chronic heart failure and kidney failure. Methods 30 patients of chronic heart failure with kidney failure were treated with valsartan 80mg/d for 4 weeks.Then measured the serum creatinine before the therapy and after the therapy.Results The clinic symptom of chronic heart faitture reduced after treated 4 weeks.The serum creatinine level evidently reduced(P<0.01).Conclusion Valsartan can improve the clinic symptoms effectively.It can safely be used in patients with chronic heart failure and kidney failure.
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