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原发性中枢神经系统淋巴瘤临床病理分析
引用本文:冯绍平,向德兵,郑华,冯家龙,刘中洪.原发性中枢神经系统淋巴瘤临床病理分析[J].武警医学院学报,2006,15(5):450-452,i0001.
作者姓名:冯绍平  向德兵  郑华  冯家龙  刘中洪
作者单位:1. 武警重庆总队医院病理科,重庆,400061
2. 第三军医大学大坪医院野战外科研究所病理科,重庆,400042
3. 武警重庆总队医院脑外科,重庆,400061
摘    要:目的]探讨原发性中枢神经系统淋巴瘤的临床病理特征。方法]对26例原发性中枢神经系统淋巴瘤的临床病理、组织化学和免疫组织化学进行分析并复习相关文献。结果]26例患者中男性15例,女性11例,平均年龄58.5岁。肿瘤位于额叶11例,顶叶8例,颞叶4例,胼胝区2例,小脑蚓部1例。26例患者瘤细胞均表达LCA、CD20或CD79a,但均不表达EBV。结论]原发性中枢神经系统淋巴瘤有其独特的临床病理特征,熟悉其临床病理特征对避免误诊具有重要意义。

关 键 词:肿瘤  中枢神经系统  淋巴瘤  病理学
文章编号:1008-5041(2006)05-0450-03
收稿时间:2006-01-13
修稿时间:2006-05-02

Clinicopathological study of primary central nervous system lymphoma
FENG Shao-ping,XIANG De-bing,ZHENG Hua,FENG Jian-long,LIU Zhong-hong.Clinicopathological study of primary central nervous system lymphoma[J].Acta Academiae Medicinae CPAPF,2006,15(5):450-452,i0001.
Authors:FENG Shao-ping  XIANG De-bing  ZHENG Hua  FENG Jian-long  LIU Zhong-hong
Abstract:Objective] To explore the clinicopathological features of primary central nervous system malignant lymphoma (PCNSL). Methods] 26 cases of PCNSL were investigated by clinicopathological analysis, histochemical and immuno-histochemical stains and review of the literature. Results] Among the 26 cases of PCNSL, there were 15 male and 11 female, with age ranges from 24 ~ 73 years (mean 58. 5 years). The neoplasm was located in lobus frontalis (11 cases), lobus parietalis ( 8 cases), lobus temporalis (4 cases), callosal area (2 cases), Cerebellar vermis (1 case). Im-munohistochemical stain showed positive for LCA, CD20 or CD79a but negative for EBV in tumor cells. Conclusion] PCNSL has a distinct clinicopathological appearance. Recognizing its clinicopathological appearance is important to avoid the confusion with other similar lesions.
Keywords:Neoplasm  Central nervous system  Lymphoma  Pathology
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