2014-2016年合肥市城市居民肺癌筛查率及筛查结果分析

目的 分析2014—2016年合肥市城市居民肺癌筛查率及筛查结果,评价肺癌筛查效果。方法 采取整群抽样的方法,对合肥市7个区40~69岁常住居民进行癌症危险因素问卷调查和肺癌高危因素评估,对评估出的肺癌高危人群进行胸部低剂量螺旋CT检查。分析肺癌高危人群筛查率和检出率。采用主动随访加被动随访统计确诊肺癌数,计算肺癌发病密度。结果 2014—2016年共完成58 105人的问卷调查和肺癌高危风险评估,评估出肺癌高危12 449人,肺癌高危率为21.43%。共5 646人参加低剂量螺旋CT筛查(筛查参与率为45.35%),检出肺部结节1 540人(结节检出率为27.28%),阳性结节354人(阳性结节检出率为6.27%),疑似肺癌54人(疑似肺癌检出率为0.96%)。评估为肺癌高危者的肺癌发病密度为131.01/10万人年;CT筛查者中检出阳性结节的肺癌发病密度为1 255.36/10万人年;CT筛查者中检出阴性结节的肺癌发病密度为103.12/10万人年。结论 低剂量螺旋CT可有效发现肺内结节及相关病变,需进一步完善筛查机制,提高肺癌高危人群筛查率,提高筛查效果及防控水平。

Analysis of lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016

Objective The aim of this study was to analyze the lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016,and evaluate the effect on lung cancer screening.Methods A cluster sampling method was used to conduct a cancer risk factor questionnaire survey and an assessment of lung cancer risk factors among permanent residents aged 40~69 years old in seven districts of Hefei city.The chest low-dose spiral computed tomography(LDCT)examination was performed on the assessed high-risk population of lung cancer.The screening rate and detection rate of high-risk population were analyzed.The active follow-up and passive follow-up were used to count the number of confirmed lung cancers and calculate the incidence density of lung cancer.Results A total of 58 105 questionnaires and high-risk assessment of lung cancer were completed from 2014 to 2016,and 12 449 people were assessed at high-risk for lung cancer.The high risk rate of lung cancer was 21.43%.A total of 5 646 people participated LDCT screening(the screening participation rate was 45.35%),1 540 people were detected for lung nodules(the nodule detection rate was 27.28%),354 people were positive for nodules(the positive nodules was 6.27%)and 54 people were suspected of lung cancer(the detection rate of suspected lung cancer was 0.96%).The incidence density of lung cancer in high risk of lung cancer patients was 131.01 per 100 000 person-year.The incidence density of lung cancer with positive nodules in CT screeners was 1 255.36 per 100 000 person-year.The incidence density of lung cancer with negative nodules in CT screeners was 103.12 per 100 000 person-year.Conclusion LDCT can effectively find nodules and related lesions in the lung.It is necessary to further improve the screening mechanism,improve the screening rate of lung cancer in high-risk groups,and improve the screening effect on the level of cancer prevention and control.