心理支持对冠心病伴抑郁患者心率震荡的影响

目的 探讨心理支持对冠心病合并抑郁患者心率震荡的影响。方法 选择在我院心内科住院及门诊确诊的冠心病患者110例,应用Zung抑郁自评量表评定抑郁状况。其中有50例冠心病伴抑郁患者被选为研究对象。50例患者随机分为观察组25例和对照组25例。观察组在常规药物治疗基础上辅以心理支持疗法。所有入选患者均接受动态心电图检查,分别于入选后当日及治疗后2周测量窦性心率震荡的参数TO、TS及SDS评分。结果 观察组患者抑郁症状较对照组进一步改善,心率震荡进一步增强。结论 冠心病合并抑郁患者心率震荡明显减弱,联合药物治疗和心理干预可进一步提高患者的心率震荡,改善迷走神经的功能,进一步改善预后。

Effect of psychological support on heart rate turbulence in patients with coronary heart disease accompanied with depression

Objective To investigate the effect of psychological support on heart rate turbulence(HRT) in patients with coronary heart disease accompanied with depression. Methods One hundred and ten outpatients and inpatients with coronary heart disease in the Department of Cardiology of our hospital were enrolled and their depression status were assessed by Zung’s self-rating depression scale(SDS). Fifty patients with coronary heart disease complicated with depression were chosen as the subject investigated. Fifty cases were randomly divided into observation group(25 cases) and control group(25cases). Besides conventional drugs,the observation group accepted psychological support treatments. All enrolled patients were performed 24-hour ambulatory electrocardiography. Their HRT parameters including HRT onset(TO) and HRT slope(TS) and SDS scores were measured,respectively one week after being chosen and two weeks after being treated. Results Compared with the control group,the depression status of the observation group was improved and HRT was enhanced further. Conclusion HRT of patients with coronary heart disease complicated with depression shows significant decrease. Combining drug therapy with psychological support can elevate patients’ HRT,improve the function of vagus nerve and the prognosis.