| 慢性自发性荨麻疹患者血清25(OH)D和IL-25水平检测 |
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| 引用本文： | 韩钰,王娟,张亚丽,贾雪松.慢性自发性荨麻疹患者血清25(OH)D和IL-25水平检测[J].中国麻风皮肤病杂志,2018,34(5):287-289. |
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| 作者姓名： | 韩钰 王娟 张亚丽 贾雪松 |
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| 作者单位： | 石河子大学第一附属医院皮肤科 新疆维吾尔族自治区 石河子832000 |
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| 摘 要： | 目的：检测慢性自发性荨麻疹( CSU)患者血清中25(OH) D和IL-25的水平。方法：电化学发光方法和ELISA分别检测40例CSU患者及30例健康对照血清中的25(OH)D和IL-25水平。结果：CSU组血清25(OH) D水平为(19.48±7.41) ng/ mL低于对照组的(23.23±6.43) ng/mL，（P<0.05）。CSU组血清IL-25水平 为(124.59±19.32) pg/ mL高于对照组的(107.33±14.57) pg/ mL,差异有统计学意义(P<0.05)。结论：血清25(OH)D和IL-25水平可能与CSU发病相关。
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| 关 键 词： | 慢性自发性荨麻疹 25羟基维生素D 白介素25 |
Detection of Serum 25-hydroxyvitamin D and IL-25 in the patients with chronic spontaneous urticaria |
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| HAN Yu,WANG Juan,ZHANG Yali,JIA Xuesong.Detection of Serum 25-hydroxyvitamin D and IL-25 in the patients with chronic spontaneous urticaria[J].China Journal of Leprosy and Skin Diseases,2018,34(5):287-289. |
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| Authors: | HAN Yu WANG Juan ZHANG Yali JIA Xuesong |
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| Affiliation: | Department of Dermatology, the First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang, 83200 |
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| Abstract: | Objective: To detect the levels of 25-hydroxy vitamin D and IL-25 in the patients with chronic spontaneous urticaria (CSU). Methods: The levels of 25(OH) D and IL-25 were detected by electrochemiluminescence and ELISA respectively in 40 patients and 30 healthy controls. Results: The serum levels of 25(OH) D and IL-25 in the patients were 19.48±7.41 ng/mL and 124.59±19.32 pg/mL, while the levels of 25(OH) D and IL-25 were 23.23±6.43ng/mL and 107.33±14.5 in the healthy controls, with significant differences (Ps<0.05). Conclusion: The levels of serum 25 (OH) D and IL-25 may be associated with the pathogenesis of CSU. |
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| Keywords: | chronic spontaneous urticaria 25(OH) D IL-25 |
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