Fetal lung growth after tracheal ligation is not solely a pressure phenomenon |
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Authors: | K Papadakis FI Luks ME De Paepe GJ Piasecki CW Wesselhoeft |
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Affiliation: | The Department of Pathology, New York University Medical Center, New York, USA. |
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Abstract: | We investigated cell proliferation and cell death in the olfactory epithelium (OE) of mice from birth to maturity using bromodeoxyuridine and terminal deoxynucleotidyl transferase nick end labeling. We show that cell death events and proliferative activity diminish concomitantly with age in the OE. Thus, the age-dependent and coordinate diminution in cell proliferative activity and cell death events may serve to maintain the thickness of the OE as mice mature and age. |
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