青岛地区供血者巨细胞病毒特异性抗体检测

我们采集青岛地区344名供血者单份血清做巨细胞病毒(HCMV)感染状况调查。用IFA测HCMV-IgG,ELISA测HCMV-IgM、HCMV-IgA。其抗体阳性率分别为99.45%、4.65%和3.20%。结果表明青岛地区供血者HCMV感染普遍,活动性感染的发生率高于国外的报道。根据目前的状况,以HCMV-IgG做为筛选供血者的指标是不现实的。

Detection of Specific Antibodies to Cytomegalovirus in the Blood Donors in Qingdao

The detection of cytomegalovirus (CMV) infection in the blood donors in China has not been reported the literature available at hands. 344 serum samples from healthy blood donors in Qingdao were examined for the presence of CMV-IgG by IFA and CMV-IgM, CMV-IgA by ELISA. The frequency of positive donors was 99,45%, 4,65%, and 3,20%, respectively. The result showed CMV infection was rather common in the donors, the rate of active CMV infection was also higher than that abroad. We suggest that when blood is transfused to high risk patients, CMV-IgM and CMV-IgA should be examined regularly on donors to exclude or reduce the incidence of transfusion-associated CMV infection. At present it is not practical for CMV-IgG as a screening marker in our country.